DNA as a quantum system in evolution
Nahuel Aquiles Garcia, Yang (Jack) Lu, Yang (Jack) Lu, Yang (Jack) Lu

TL;DR
This paper proposes a quantum model of DNA where time and entropy influence mutation probabilities during replication and repair.
Contribution
A novel quantum-information model linking DNA dynamics to cosmic time through entropy and weak perturbations.
Findings
Genomic segments show distinct dynamical signatures under physiologically plausible perturbations.
Sequence-dependent responses to perturbations suggest reproducible shifts in mutation spectra.
The model connects biological processes like aging to cosmic time through quantum effects.
Abstract
Time may be viewed as an emergent consequence of increasing information entropy. I explore a toy quantum‑information model in which DNA is treated as an open quantum system. In this framework, weak, time‑dependent perturbations (potentially arising from thermal fluctuations, ionic microfields, metabolic noise, or electromagnetic signals) bias the micro‑timing of events during replication and repair. These slight timing shifts can influence the fate of transient electronic and protonic configurations (including short‑lived tautomeric states driven by proton‑transfer tunnelling), subtly altering mutation probabilities. To test this idea, I map nucleotides in the Mycobacterium tuberculosis genome to constrained qubit states and quantify informational structure using Shannon and von Neumann entropies and coding to non‑coding correlation metrics. Simulations of Hamiltonian dynamics under…
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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Taxonomy
TopicsOrigins and Evolution of Life · Fractal and DNA sequence analysis · Space Science and Extraterrestrial Life
