# Host jumps need not be common just because spillover is

**Authors:** Mete Yuksel, Nicole Mideo

PMC · DOI: 10.1371/journal.pbio.3003682 · 2026-03-20

## TL;DR

A new study suggests that frequent spillover of pathogens does not necessarily mean they are more likely to cause pandemics.

## Contribution

The study challenges the assumption that high spillover frequency correlates with higher emergence risk.

## Key findings

- Pathogens that frequently spill over are not necessarily more likely to emerge as pandemic threats.
- Emergence risk depends on more than just the frequency of spillover events.

## Abstract

Can we predict which pathogen will be responsible for the next pandemic? Emergence risk is a hotly debated topic and a new study in PLOS Biology challenges the idea that pathogens that frequently spill over are more likely to emerge.

Can we predict which pathogen will be responsible for the next pandemic? Emergence risk is a hotly debated topic and a new study in PLOS Biology challenges the idea that pathogens that frequently spill over are more likely to emerge.

## Full-text entities

- **Diseases:** infectious diseases (MESH:D003141)
- **Species:** Severe acute respiratory syndrome coronavirus 2 (no rank) [taxon 2697049], Homo sapiens (human, species) [taxon 9606], Viruses (acellular root) [taxon 10239], H5N1 subtype (serotype) [taxon 102793]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC13004401/full.md

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Source: https://tomesphere.com/paper/PMC13004401