# Midline congenital upper lip sinus: a rare clinical case with analytical review of diagnostic and therapy strategies

**Authors:** Shuang Yang, Kai Kang, Wei Liu, Zhibo Zhou

PMC · DOI: 10.3389/fped.2026.1777126 · 2026-03-06

## TL;DR

This paper presents a rare case of a congenital upper lip sinus and reviews its diagnosis and treatment strategies.

## Contribution

The paper adds a new clinical case of a midline upper lip sinus to the limited existing literature.

## Key findings

- The sinus presented as a whitish discharge in the middle of the philtrum.
- There are very few reported cases of upper lip sinuses in China.
- The condition is often isolated without intra-oral communication.

## Abstract

Congenital midline sinus of the upper lip is rarest malformation with or without other anomalies. Mostly the sinus opens below the white role on the vermilion and has no intra-oral communication. To date, there have been only several case reports of upper lip sinuses associated with other anomalies, such as cleft palate or transverse facial cleft in China. We herein present a case of congenital upper lip sinus in the middle of the philtrum presenting as whitish discharge used to come out of it and review the current literature on this condition.

## Full-text entities

- **Diseases:** sinuses (MESH:D012852), transverse facial cleft (MESH:D008265), Congenital midline sinus of the upper lip (MESH:C563907), upper (MESH:D012141), upper lip sinus (MESH:D008047), cleft palate (MESH:D002972)

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13003570/full.md

---
Source: https://tomesphere.com/paper/PMC13003570