# Robotic-integrated intraoperative ultrasound for excision of accessory cavitated uterine malformation (ACUM): an innovative surgical technique

**Authors:** Smitha Priyadarshini Thippeswamy, Radwa Hablase, Joydeep Chatterjee, Raef Faris, Priya Narayanan, Jayanta Chatterjee

PMC · DOI: 10.1007/s00404-026-08395-2 · 2026-03-19

## TL;DR

A new robotic-assisted surgical technique using intraoperative ultrasound improves precision in removing rare uterine anomalies while preserving healthy tissue.

## Contribution

Integrates robotic intraoperative ultrasound for real-time guidance in excising ACUM, enhancing precision and tissue preservation.

## Key findings

- The robotic-integrated intraoperative ultrasound enabled real-time identification of lesion margins and vascular mapping.
- The technique preserved endometrial cavity integrity and minimized myometrial tissue loss.
- The patient experienced complete symptom resolution post-surgery.

## Abstract

Accessory cavitated uterine mass (ACUM) is a rare Mullerian anomaly that predominantly affects young women, presenting with refractory dysmenorrhea. Despite 3D ultrasound and MRI being the gold standard for diagnosis, diagnostic delays and accuracy limitations continue to hinder timely management. The deep intra-myometrial location of this anomaly poses significant surgical challenges in achieving complete excision while preserving healthy myometrium.

A 22-year-old nulliparous woman presented with incapacitating cyclical pelvic pain and was diagnosed with ACUM. She underwent surgical management using a novel robotic-assisted technique.

The procedure utilised robotic-integrated intraoperative ultrasound via a drop-in probe, enabling real-time identification of lesion margins, vascular mapping, and confirmation of complete lesion excision. This approach minimised loss of healthy myometrium and preserved endometrial cavity integrity.

The patient reported complete symptom resolution postoperatively. Integration of real-time intraoperative ultrasound within the robotic platform enhanced surgical precision, reduced surgical trauma, and has the potential to improve reproductive outcomes.

Robotic-assisted excision of ACUM with intraoperative ultrasound guidance represents an innovative and precise surgical technique. This approach addresses the key challenges of lesion localisation and myometrial preservation, offering a promising strategy for managing this rare condition in women of reproductive age.

## Full-text entities

- **Genes:** IL1B (interleukin 1 beta) [NCBI Gene 3553] {aka IL-1, IL1-BETA, IL1F2, IL1beta}, TNF (tumor necrosis factor) [NCBI Gene 7124] {aka DIF, IMD127, TNF-alpha, TNFA, TNFSF2, TNLG1F}, CXCL8 (C-X-C motif chemokine ligand 8) [NCBI Gene 3576] {aka GCP-1, GCP1, IL8, LECT, LUCT, LYNAP}, IL17A (interleukin 17A) [NCBI Gene 3605] {aka CTLA-8, CTLA8, IL-17, IL-17A, IL17, ILA17}, IL6 (interleukin 6) [NCBI Gene 3569] {aka BSF-2, BSF2, CDF, HGF, HSF, IFN-beta-2}
- **Diseases:** inflammation (MESH:D007249), ACUM (MESH:D014591), Mullerian anomalies (MESH:C537371), Uterine Mass (MESH:C536030), fertility impairment (MESH:D007246), leiomyoma (MESH:D007889), dysmenorrhea (MESH:D004412), adenomyosis (MESH:D062788), pain (MESH:D010146), immune dysfunction (MESH:D007154), adenomyoma (MESH:D018194), endometriosis (MESH:D004715), uterine anomaly (MESH:C562565), bleeding (MESH:D006470), pelvic and lower abdominal pain (MESH:D015746), trauma (MESH:D014947), pelvic pain (MESH:D017699)
- **Chemicals:** progesterone (MESH:D011374), ethanol (MESH:D000431)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13002756/full.md

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Source: https://tomesphere.com/paper/PMC13002756