# Vestibular granuloma as a rare post-stapedotomy complication: case report and literature review

**Authors:** Riccardo De Lellis, Filippo Valentini, Mara Riminucci, Alessandro Corsi, Francesca Yoshie Russo, Daniele De Seta

PMC · DOI: 10.1007/s00405-025-09880-1 · European Archives of Oto-Rhino-Laryngology · 2025-11-25

## TL;DR

A rare complication called vestibular granuloma can occur after stapedotomy surgery, leading to severe symptoms and requiring careful, long-term management.

## Contribution

This case report adds to the limited literature on vestibular granuloma as a post-stapedotomy complication and emphasizes the importance of early diagnosis and multimodal treatment.

## Key findings

- Vestibular granuloma can develop after stapedotomy, causing vertigo and hearing loss.
- Early imaging and hearing assessments are critical for diagnosing and managing this complication.
- Persistent Postural-Perceptual Dizziness (PPPD) may follow granuloma removal and requires multimodal treatment.

## Abstract

Vestibular granuloma is a rare complication of a common surgical procedure, such as stapedotomy; it can significantly impact the outcome of surgery, leading to severe impairment and deterioration in the patient’s quality of life.

A 59-year-old male underwent stapedotomy with a titanium prosthesis. Initially, hearing function improved but, within days, the patient developed vertigo and worsened hearing loss. HR CT of temporal bone revealed soft tissue in the tympanic cavity, prompting revision surgery. Granulomatous tissue surrounding the prosthesis was removed, leading to symptom relief. However, the patient later developed Persistent Postural-Perceptual Dizziness (PPPD), requiring SSRI therapy.

The sudden onset of persistent vertigo and hearing loss, that rapidly worsens in post-operative setting, represents a crucial red flag for the surgical team. Hearing assessments and imaging play a key role in quickly diagnosing the cause of these complications, which may be attributed to an inflammatory response at the surgical site, possibly due to granuloma formation. This enables the surgical équipe to swiftly implement appropriate care strategies for the patient, even in the presence of additional and subsequent complications like PPPD, which requires a comprehensive, multimodal approach to treatment.

This case highlights the risk of a series of complications after surgery and even after reoperation, ultimately requiring conservative multimodal treatment and follow-up. Early recognition and coordinated care are essential for optimal long-term management of patients, even in the presence of unfavorable outcomes and complications.

## Full-text entities

- **Diseases:** Persistent (MESH:D000088562), vertigo (MESH:D014717), hearing loss (MESH:D034381), PPPD (MESH:D004244), Vestibular granuloma (MESH:D006099), inflammatory (MESH:D007249)
- **Chemicals:** titanium (MESH:D014025)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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Source: https://tomesphere.com/paper/PMC13002652