# Advances in artificial intelligence-based approaches to enhance dark field X-ray microscopy analysis

**Authors:** Brinthan Kanesalingam, Can Yildirim, Leora Dresselhaus-Marais

PMC · DOI: 10.1557/s43579-025-00860-4 · Mrs Communications · 2025-12-08

## TL;DR

This paper explores how artificial intelligence improves dark field X-ray microscopy for studying crystal dislocations in materials.

## Contribution

The paper introduces physics-informed AI methods to enhance dislocation analysis in dark field X-ray microscopy.

## Key findings

- Physics-informed AI approaches enable time-resolved dislocation dynamics studies.
- Semi-automated workflows using wavelet transforms and Bayesian inference track dislocation behavior.
- The methods successfully analyze complex dislocation networks and thermal motion in materials.

## Abstract

Dark field X-ray microscopy (DFXM) has emerged as a powerful technique for characterizing dislocations in bulk crystalline materials, whose high penetration depth and non-destructive evaluation offer unique advantages over traditional electron microscopy methods. The interpretation and analysis of the DFXM data presents significant challenges that have limited its broader adoption. Here we review our recent advances using artificial intelligence (AI) methods to enhance DFXM analysis, particularly focusing on dislocation characterization. We discuss the development of physics-informed AI approaches that combine theoretical understanding with data science techniques to enable both time-resolved dislocation dynamics studies and dimensional reduction of complex DFXM datasets. Our work demonstrates how semi-automated workflows, guided by dislocation theory and employing techniques such as wavelet transforms and Bayesian inference, can effectively track and analyze dislocation behavior across multiple time scales. These methodologies have been successfully applied to various materials science challenges, from studying thermally activated dislocation motion to characterizing dislocation networks. By presenting our works that integrate physics-based modeling into AI capabilities, we demonstrate how our and other works can extract new important quantitative dislocation data from DFXM measurements.

## Full-text entities

- **Diseases:** dislocation (MESH:D004204)

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13002649/full.md

## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC13002649/full.md

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Source: https://tomesphere.com/paper/PMC13002649