# AI-navigated shoulder injection: precision, real-time learning and clinical translation

**Authors:** Hua Li, Xiaodan Huang, Ming Zhao, Yanxin Cheng

PMC · DOI: 10.3389/frai.2026.1727704 · Frontiers in Artificial Intelligence · 2026-03-06

## TL;DR

This paper reviews how AI improves the accuracy and success of shoulder injections using ultrasound guidance, showing better patient outcomes.

## Contribution

The paper systematically evaluates AI technologies in shoulder injections, highlighting their precision and real-time learning capabilities.

## Key findings

- AI increases anatomical segmentation accuracy and first-pass puncture success rates.
- AI improves patient outcomes through enhanced injection precision and real-time learning.
- AI addresses limitations of traditional ultrasound guidance in shoulder injections.

## Abstract

This review focuses on artificial intelligence (AI)-guided ultrasound-guided shoulder joint injections. We systematically retrieved relevant studies from PubMed, Embase, Cochrane Library, IEEE Xplore, and Web of Science (1996 ~ 2025). Literature was screened based on predefined inclusion/exclusion criteria, and evaluated AI technologies using core metrics including anatomical segmentation accuracy (Dice similarity coefficient), first-pass puncture success rate, and clinical outcome indicators (Visual analogue scale scores, VAS; American Shoulder and Elbow Surgeons, ASES scores). It explores the technical principles of AI medical image processing (segmentation, detection, tracking, reconstruction) and deep learning algorithms for shoulder anatomy, addressing limitations of traditional ultrasound guidance through AI-enabled precision targeting and real-time learning. Clinical applications, technological advancements, ethical controversies, and regulatory pathways are summarized. Key findings confirm AI enhances injection accuracy, first-pass success rates, and patient outcomes. This work provides a concise, evidence-based reference for clinicians and researchers, highlighting the paradigm shift of AI in optimizing shoulder injection therapy.

## Full-text entities

- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

72 references — full list in the complete paper: https://tomesphere.com/paper/PMC13002621/full.md

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Source: https://tomesphere.com/paper/PMC13002621