# Chest pain with elevated ST segment in lead V1: a case report

**Authors:** Zhongyong He, Xiaobo Pu, Lijun Zeng

PMC · DOI: 10.3389/fcvm.2026.1731030 · Frontiers in Cardiovascular Medicine · 2026-03-06

## TL;DR

A rare case of right ventricular infarction is presented, showing how it can be distinguished from anteroseptal myocardial infarction using specific ECG patterns.

## Contribution

This case report highlights unique ECG features of isolated right ventricular infarction to aid in accurate diagnosis.

## Key findings

- The patient's ECG showed decremental STE (V1 > V2) and STE in lead III.
- Coronary angiography confirmed a proximal occlusion of the non-dominant right coronary artery.

## Abstract

Isolated right ventricular infarction (RVI) is an underrecognized clinical entity that often mimics anteroseptal myocardial infarction due to its characteristic ST-segment elevation (STE) in precordial leads. We report the case of a 55-year-old man who presented with acute chest pain and STE in leads V1 and V2. Despite typical anteroseptal infarction patterns, the electrocardiogram (ECG) revealed decremental STE (V1 > V2), concomitant STE in lead III, and reciprocal ST depression in lateral leads. Coronary angiography confirmed proximal occlusion of the non-dominant right coronary artery. This case highlights the diagnostic challenges of isolated RVI and underscores key ECG features that distinguish it from anteroseptal infarction. Early recognition is imperative to avoid detrimental therapies (e.g., vasodilators) and to prioritize reperfusion and preload optimization.

## Linked entities

- **Diseases:** myocardial infarction (MONDO:0005068)

## Full-text entities

- **Diseases:** depression (MESH:D003866), RVI (MESH:D007238), anteroseptal infarction (MESH:D056988), occlusion (MESH:D001157), Chest pain (MESH:D002637)

## Full text

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## Figures

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## References

7 references — full list in the complete paper: https://tomesphere.com/paper/PMC13002573/full.md

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Source: https://tomesphere.com/paper/PMC13002573