# Brown Tumor in a Patient With End-Stage Renal Disease: A Case Report of Secondary Hyperparathyroidism Complications

**Authors:** Ahdadi Ahmed, Hamraoui Salima, Assadiki Akram, Zakaria Mimouni, Rachid Marouf

PMC · DOI: 10.7759/cureus.103787 · Cureus · 2026-02-17

## TL;DR

A rare brown tumor developed in a patient with kidney disease despite treatment for hormone imbalance.

## Contribution

This case report highlights brown tumor complications in end-stage renal disease despite standard treatments.

## Key findings

- A 29-year-old man with end-stage renal disease developed a brown tumor in the ribs.
- Medical treatment and surgeries failed to resolve the expansive costal lesion.
- Brown tumors remain a rare complication of secondary hyperparathyroidism in kidney disease patients.

## Abstract

The development of a brown tumor is a rare complication of secondary hyperparathyroidism, particularly in patients with chronic kidney disease. Despite advances in the treatment and management of secondary hyperparathyroidism, these tumors can still occur. We report the case of a 29-year-old man with end-stage renal disease treated with hemodialysis, who developed a brown tumor in the ribs. Despite medical treatment including calcium and vitamin D supplementation, and multiple parathyroidectomies, imaging revealed an expansive and sclerotic costal lesion, confirmed as a brown tumor. Diagnosis is based on clinical, biological, and radiological evaluations. Treatments aim to reduce parathyroid hormone (PTH) levels and correct metabolic abnormalities, with parathyroidectomy as an option in cases of medical treatment failure.

## Linked entities

- **Diseases:** chronic kidney disease (MONDO:0005300), end-stage renal disease (MONDO:0004375), secondary hyperparathyroidism (MONDO:0006964)

## Full-text entities

- **Genes:** PTH (parathyroid hormone) [NCBI Gene 5741] {aka FIH1, PTH1}
- **Diseases:** Brown Tumor (MESH:D009369), metabolic abnormalities (MESH:D008659), chronic kidney disease (MESH:D051436), End-Stage Renal Disease (MESH:D007676), Secondary Hyperparathyroidism (MESH:D006962)
- **Chemicals:** calcium (MESH:D002118), vitamin D (MESH:D014807)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13002233/full.md

## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC13002233/full.md

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Source: https://tomesphere.com/paper/PMC13002233