# Zero Fluoroscopy Ablation of Arrhythmias in Patients With Congenital Heart Disease

**Authors:** Shailendra Upadhyay, Jenna Schermerhorn, Whitney Fairchild, Jamie Bopp, Irfan Warsy

PMC · DOI: 10.1002/joa3.70225 · Journal of Arrhythmia · 2025-11-17

## TL;DR

This study shows that catheter ablation for heart rhythm disorders in patients with congenital heart disease can be done safely and effectively without using X-ray imaging.

## Contribution

The study demonstrates the feasibility and safety of zero-fluoroscopy ablation in a diverse group of congenital heart disease patients.

## Key findings

- 42 patients with congenital heart disease underwent successful zero-fluoroscopy ablation with 100% acute success.
- There were no acute complications and low recurrence rates over a 48-month follow-up.
- The approach eliminated radiation exposure while maintaining safety and effectiveness.

## Abstract

Radiation‐free catheter ablation is feasible with modern electroanatomic mapping systems. We aimed to evaluate the feasibility, safety, and outcomes of non‐fluoroscopic ablation (NFA) in patients with congenital heart disease (CHD).

We retrospectively reviewed CHD patients who underwent NFA between November 2016 and January 2025. All procedures were performed using the CARTO 3D electroanatomic mapping system. Atrial, ventricular, and aortic geometries were reconstructed as needed. Catheter navigation and sheath placement were guided without fluoroscopy; intracardiac echocardiography was used selectively.

Forty‐two patients (23 females) with CHD underwent NFA. The median age was 14 years (range 4–56), and median weight was 55 kg (range 19–145). Twenty‐one patients had mild, 16 moderate complexity and 5 great complexity CHD. Arrhythmia mechanisms included AVNRT (14%), manifest WPW (21%), high‐risk WPW without SVT (5%), concealed pathway AVRT (26%), AFL (12%), AT (14%), and VT (7%). Two patients had both AVNRT and AVRT. Acute success was achieved in all cases without fluoroscopy or acute complications. Over a median 48‐month follow‐up, three patients had recurrences: one with WPW and Ebstein anomaly, one with ASD/PLSVC and concealed pathway, and one with dual arrhythmia substrates.

Zero‐fluoroscopy ablation of arrhythmias in select patients with mild moderate or great complexity CHD is feasible, safe, and effective, offering high acute success and low recurrence while eliminating radiation exposure.

Zero‐fluoroscopy radiofrequency ablation using 3D electroanatomic mapping was performed in 42 patients with mild, moderate, or great complexity congenital heart disease. Acute success was 100%, with no complications and minimal recurrence over 48 months. This approach eliminates radiation exposure while maintaining safety and efficacy across select yet diverse CHD anatomies.

## Linked entities

- **Diseases:** congenital heart disease (MONDO:0005453), WPW (MONDO:0008685), Ebstein anomaly (MONDO:0009144), ASD (MONDO:0006664), AT (MONDO:0008840)

## Full-text entities

- **Diseases:** ASD (MESH:D001321), WPW (MESH:D014927), CHD (MESH:D006330), PLSVC (MESH:D000083402), Arrhythmia (MESH:D001145), Ebstein anomaly (MESH:D004437)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13001673/full.md

## References

27 references — full list in the complete paper: https://tomesphere.com/paper/PMC13001673/full.md

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Source: https://tomesphere.com/paper/PMC13001673