# The Impact of Rurality on Substance Use and Adverse Mental Health Among High School Students in Vermont, USA: A Cross-Sectional Study

**Authors:** Olivia Tarmey, Gina Neidig, Anna Cosentino, Natalie Hewitt, Chike Asanya, Thomas V Delaney, Elzerie De Jager

PMC · DOI: 10.7759/cureus.103767 · Cureus · 2026-02-17

## TL;DR

This study examines how rurality affects the link between substance use and poor mental health in Vermont high school students.

## Contribution

The study investigates whether rurality modifies the relationship between substance use and mental health in adolescents.

## Key findings

- Adverse mental health was associated with substance use in both rural and non-rural students.
- The relationship between mental health and substance use did not significantly differ by rurality.

## Abstract

Introduction

Rates of poor mental health among high school students in the United States are increasing. Both substance use and rurality are independently associated with poor mental health outcomes among adolescents. This study explores the impact that rurality may have on the relationship between substance use and poor mental health outcomes among Vermont high schoolers.

Methods

The 2021 Vermont Youth Risk Behavior Survey (YRBS) was used (N = 15,097). Multivariate logistic regression was used to assess the relationship between adverse mental health and substance use by rurality.

Results

Experiences of adverse mental health were associated with substance use behaviors among rural and non-rural populations. The associations between adverse mental health and substance use variables did not significantly vary by rurality.

Conclusions

Rural environments may not modify the relationship between adverse mental health and substance use. Future research is needed to understand the causal mechanisms between adverse mental health and substance use and how these may differ by rurality.

## Full-text entities

- **Diseases:** Mental Health (OMIM:603663)

## Full text

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## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC13001528/full.md

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Source: https://tomesphere.com/paper/PMC13001528