# LRP4 ‐Related Lethal Syndromic Form of Syndactyly in Limousin Cattle

**Authors:** Joana Jacinto, Jessica Gearing, Aurélien Capitan, Ana‐Maria Zorlescu, Arthur Otter, Cord Drögemüller

PMC · DOI: 10.1002/age.70090 · Animal Genetics · 2026-03-19

## Full-text entities

- **Genes:** LRP4 (LDL receptor related protein 4) [NCBI Gene 504317] {aka MEGF7}, AGRN (agrin) [NCBI Gene 525795], LDLR (low density lipoprotein receptor) [NCBI Gene 281276]
- **Diseases:** Cenani-Lenz syndactyly syndrome (MESH:C538150), kidney anomalies (MESH:D007674), Syndactyly (MESH:D013576), congenital myasthenic syndromes (MESH:D020294), Diseases of (MESH:D004194), facial dysmorphism (MESH:C565579), polydactyly (MESH:D017689), syndromic (MESH:D013577), arthrogryposis (MESH:D001176), congenital abnormalities (MESH:D000013), skeletal disorders (MESH:C564967)
- **Chemicals:** cystine (MESH:D003553), metal (MESH:D008670)
- **Species:** Bovine viral diarrhea virus 1 (no rank) [taxon 11099], Schmallenberg virus (no rank) [taxon 1133363], Bos taurus (bovine, species) [taxon 9913], Homo sapiens (human, species) [taxon 9606]
- **Mutations:** g.76826546C>A, p.Cys57Phe, c.170G>T

## Full text

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## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC13001133/full.md

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Source: https://tomesphere.com/paper/PMC13001133