# The role of abnormal amino acid metabolism in the occurrence and development of tumors

## TL;DR

This paper reviews how tumor cells use amino acid metabolism to grow and how this process affects immune cells, offering insights for cancer treatment.

## Contribution

The paper provides a comprehensive review of amino acid metabolism in tumors and its impact on immune cells.

## Key findings

- Tumor cells rely on unique metabolic pathways to uptake essential amino acids.
- Abnormal amino acid metabolism supports tumor proliferation and immune cell inhibition.
- Understanding these pathways could lead to targeted cancer treatments.

## Abstract

The proliferation, migration, and invasion of tumor cells require a large amount of nutrients. Among them, the uptake of amino acids is crucial for most cellular functions, such as protein synthesis and cell growth. Tumor cells obtain a large number of essential amino acids from the environment through unique metabolic pathways and accelerate the synthesis of non-essential amino acids to meet their own needs. This review summarizes the uptake and utilization of amino acids by tumors and their inhibitory effects on immune cells, providing a basis for targeted metabolism in cancer treatment.