# Preferences for Social Media Vaccination Messaging

**Authors:** Lucía Abascal Miguel, Alison B. Comfort, Alicia R. Riley, Gilberto Lopez, Janelli Vallin, Anna E. Epperson, Nadia Diamond-Smith

PMC · DOI: 10.1001/jamanetworkopen.2026.2284 · JAMA Network Open · 2026-03-18

## TL;DR

People prefer social media vaccine posts that are factual and from trusted sources like public health agencies or healthcare workers.

## Contribution

The study introduces innovative methods like discrete choice experiments to understand preferences for vaccine-related social media content.

## Key findings

- Factual posts from public health organizations are more preferred than humorous or unsourced ones.
- Posts featuring healthcare workers or older adults are more likely to be preferred.
- Visual content like pictures and short videos are commonly preferred by participants.

## Abstract

This cross-sectional study identifies the attributes of vaccination-related posts on social media associated with audience engagement.

Which characteristics of social media vaccination posts do audiences prefer when deciding which content to engage with?

In this cross-sectional study of 243 adults in California, social media vaccination posts that were factual and from trusted public health organizations and health care workers were significantly more likely to be preferred than humorous or unsourced posts. The artwork type of a post showed no significant association with preference.

Findings from this study suggest that innovative experimental methods, such as discrete choice experiment, can inform the design of digital public health communication.

Social media is a dominant source of health information, including vaccine information, but little is known about which message characteristics audiences prefer when deciding what social media content to engage with and about how to measure these preferences.

To quantify the attributes of existing social media vaccination posts that are associated with the preference for and confidence in vaccination-related content.

This cross-sectional study used a combination of the discrete choice experiment (DCE) and the Swiss tournament approaches to evaluate preferences, which were collected in an online survey between March and May 2024. Participants (aged ≥18 years) from a previous California-based COVID-19 study were recontacted through social media between January and August 2024. Participants completed the DCE and Swiss tournament test.

Participants viewed pairs of vaccination-related social media posts that varied systematically by attributes, such as messenger, source, tone, artwork type, age group of messenger, and topic.

Participants selected which post they were most likely to engage with (like, share, or comment). Preferences were analyzed using a conditional logit model to estimate relative importance of post attributes.

Among 243 participants (mean [SD] age, 36.4 [12.4] years; 127 males [52.5%]), 153 (63.0%) reported favorable attitudes toward vaccines in general, 167 (68.7%) toward influenza vaccines, and 117 (48.2%) toward COVID-19 vaccines. Daily social media use was common (228 [93.8%]), and most participants preferred visual content, such as pictures (206 [84.8%]) or short videos (184 [75.7%]). In the DCE, social media vaccination posts from public health agencies such as California Department of Public Health (adjusted odds ratio [AOR], 1.80; 95% CI, 1.57-2.07) and University of California San Francisco (AOR, 1.67; 95% CI, 1.21-2.29) and posts depicting health care workers (AOR, 1.28; 95% CI, 1.12-1.47) or older adults (AOR, 1.48; 95% CI, 1.22-1.80) were more likely to be preferred. Humorous tone was associated with reduced preference (AOR, 0.45; 95% CI, 0.36-0.57), whereas COVID-19 (AOR, 2.35; 95% CI, 1.95-2.87) and influenza (AOR, 1.78; 95% CI, 1.54-2.06) topics were associated with increased likelihood for preference. Artwork type showed no significant association with preference.

This cross-sectional study found that participants preferred social media–based vaccination posts that were factual, featured health care professionals, and were sourced from public health organizations. Understanding communication preferences through innovative experimental methods can inform the design of digital public health communications.

## Full-text entities

- **Diseases:** Influenza (MESH:D007251), COVID-19 (MESH:D000086382), heart complications (MESH:D006331), deaths (MESH:D003643)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

29 references — full list in the complete paper: https://tomesphere.com/paper/PMC13000627/full.md

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Source: https://tomesphere.com/paper/PMC13000627