# Advances in the Use of Microwaves for Isolation and Structural Modification of Biobased Polysaccharides

**Authors:** Euda Maria Gomes dos Santos, Expedito Lopes Fernandes Júnior, Gabrielle de Lima Maniçoba, Amanda Damasceno Leão, Antônia Carla de Jesus Oliveira, Luíse Lopes Chaves, Monica Felts De La Roca Soares, José Lamartine Soares-Sobrinho

PMC · DOI: 10.1021/acsomega.5c11982 · ACS Omega · 2026-03-04

## TL;DR

Microwaves offer a fast, energy-efficient, and eco-friendly way to extract and modify plant-based polysaccharides for use in various industries.

## Contribution

The paper highlights microwave technology as a novel and sustainable method for isolating and modifying biobased polysaccharides.

## Key findings

- Microwaves reduce reaction times and energy use while improving the purity of extracted polysaccharides.
- Microwave-assisted modification enhances solubility and antimicrobial properties of polysaccharides.
- Microwave processes lower carbon footprint and support sustainable industrial practices.

## Abstract

Microwave technology has become a prominent and sustainable
method
for isolating and chemically modifying natural polysaccharides, mainly
from plant biomass. It offers rapid, uniform, and selective heating,
significantly reducing reaction times and energy use compared with
traditional methods. During isolation, microwaves enable the effective
extraction of high-purity polysaccharides using smaller amounts of
milder solvents, aligning with green chemistry principles. For chemical
modifications, microwave activation enhances reaction efficiency,
lowers reagent consumption, and minimizes byproduct formation. These
improvements produce polysaccharides with enhanced properties, such
as increased solubility, antimicrobial activity, and tailored functionalities,
broadening their use in food, cosmetics, pharmaceuticals, and biodegradable
packaging industries. Compared with conventional heating, microwave-assisted
processes have been reported to reduce energy demand and the associated
carbon footprint. Future developments include integrating microwaves
with other activation techniques such as ultrasound or enzymatic catalysis
to boost efficiency and selectivity. Utilizing residual biomass as
a polysaccharide source also presents a promising route toward sustainable
and circular economy practices, meeting rising demands for eco-friendly
materials and clean technologies. Overall, microwave-assisted processes
are establishing themselves as vital tools in green chemistry, driving
innovation in renewable materials and sustainable industrial applications.

## Full-text entities

- **Chemicals:** polysaccharide (MESH:D011134), Biobased Polysaccharides (-), carbon (MESH:D002244)

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13000622/full.md

## References

144 references — full list in the complete paper: https://tomesphere.com/paper/PMC13000622/full.md

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Source: https://tomesphere.com/paper/PMC13000622