# B-mode and contrast-enhanced ultrasound versus magnetic resonance imaging in hepatic angiomyolipoma: a case report

**Authors:** Andrea Balbinot, Sofia Maria Bakken, Nicola Venturoli, Deborah Malvi, Elisa Albertini, Maria Giulia Pirini, Antonietta D’Errico, Carla Serra

PMC · DOI: 10.1007/s40477-025-01015-w · 2025-04-28

## TL;DR

This case report compares ultrasound and MRI in diagnosing a rare liver tumor in a patient with a genetic condition.

## Contribution

The study highlights the diagnostic value of B-mode and contrast-enhanced ultrasound in hepatic angiomyolipoma.

## Key findings

- B-mode and contrast-enhanced ultrasound correctly identified a benign hepatic lesion.
- MRI initially suggested hepatocellular carcinoma, but ultrasound findings were confirmed by histology.
- HAML is rare and can be challenging to diagnose, but ultrasound may aid in accurate assessment.

## Abstract

Angiomyolipoma is a solid mesenchymal tumour that usually affects the kidney. Hepatic localization of angiomyolipoma (HAML) is rare and usually asymptomatic however it presents a challenging differential diagnosis. We present the case of a 45-year-old man affected by tuberous sclerosis complex type 2 (TSC2) and an hepatic lesion suspected to be hepatocellular carcinoma on magnetic resonance but whose Bmode ultrasound and contrast-enhanced ultrasound (CEUS) findings were consistent with benignity, as confirmed by histology.

## Linked entities

- **Diseases:** hepatocellular carcinoma (MONDO:0007256), angiomyolipoma (MONDO:0002603)

## Full-text entities

- **Genes:** TSC2 (TSC complex subunit 2) [NCBI Gene 7249] {aka LAM, PPP1R160, TSC4}
- **Diseases:** hepatocellular carcinoma (MESH:D006528), mesenchymal tumour (MESH:D008637), hepatic lesion (MESH:D056486), Angiomyolipoma (MESH:D018207)

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13000067/full.md

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Source: https://tomesphere.com/paper/PMC13000067