# Clinical application of the F21 multipurpose cystoscope with continuous irrigation capability

**Authors:** Guihua Cao, Tao Ma, Liangcheng Liu, Wei Li, Qiang Li, Jianping Du

PMC · DOI: 10.3389/fsurg.2026.1680966 · 2026-03-05

## TL;DR

A new F21 cystoscope with continuous irrigation was tested for safety and effectiveness in urologic procedures like stent removal and prostate treatment.

## Contribution

The study introduces a small-caliber F21 cystoscope with continuous irrigation for urologic procedures, demonstrating its safety and effectiveness.

## Key findings

- The F21 cystoscope successfully completed all stent removals and catheterizations without complications.
- PVP procedures using the cystoscope showed significant improvements in urinary flow and symptom scores.
- No major complications were observed in patients at 3 and 6 months post-procedure.

## Abstract

To evaluate the safety and clinical performance of an F21 multipurpose cystoscope equipped with a continuous irrigation system in routine urologic procedures.

This single-center retrospective study consecutively enrolled 150 patients undergoing F21 multipurpose cystoscope–assisted procedures (50 double-J stent removals, 50 retrograde 5-Fr ureteral catheterizations, and 50 BPH patients receiving PVP).BPH patients had bladder outlet obstruction (Qmax <10 mL/s), and major exclusions included prostate cancer and prostate volume >80 mL.Outcomes included procedure-related complications; IPSS and Qmax were assessed preoperatively and at 3 and 6 months in the PVP cohort.

All double-J stent removals and retrograde catheterizations were completed successfully under local anesthesia with a consistently clear operative field, and no postoperative complications were observed. All 50 PVP procedures were completed successfully; mean operative time was 65.1 ± 16.9 min, blood loss was <60 mL, postoperative irrigation averaged 17 h, and catheter removal occurred on postoperative days 3–5. In the PVP group, Qmax increased from 6.314 preoperatively to 21.716 at 3 months and 21.006 at 6 months, while IPSS decreased from 23.540 to 4.700 and 4.420, respectively (all p < 0.001). At the 3-month and 6-month postoperative follow-up time points, none of the patients developed complications such as urinary incontinence, urethral stricture, bladder neck contracture, or voiding dysfunction.

The F21 multipurpose cystoscope with continuous irrigation provides stable visualization and supports both routine cystoscopic interventions and PVP in a small-caliber platform, demonstrating favorable safety and functional outcomes.

## Linked entities

- **Diseases:** benign prostatic hyperplasia (MONDO:0010811), prostate cancer (MONDO:0005159)

## Full-text entities

- **Diseases:** blood (MESH:D006402), bladder neck contracture (MESH:D003286), urinary incontinence (MESH:D014549), prostate cancer (MESH:D011471), urethral stricture (MESH:D014525), bladder outlet obstruction (MESH:D001748), voiding dysfunction (MESH:C537271)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12999935/full.md

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Source: https://tomesphere.com/paper/PMC12999935