# Exploring associations between area deprivation index, income, and loneliness among cancer caregivers

**Authors:** Kyle Pitzer, JoAnn Jabbari, George Demiris, Ramy Sedhom, Jacquelyn J. Benson, Debra Parker Oliver, Karla T. Washington

PMC · DOI: 10.1007/s00520-026-10578-1 · 2026-03-18

## TL;DR

This study explores how neighborhood deprivation and income affect loneliness in cancer caregivers, finding that lower income is linked to higher loneliness.

## Contribution

The study identifies income as a significant factor in loneliness among cancer caregivers, independent of neighborhood deprivation.

## Key findings

- Caregivers with household incomes below $70,000 experience higher loneliness than those with higher incomes.
- No significant association was found between area deprivation index and loneliness.
- No interaction effect was detected between area deprivation index and income on loneliness.

## Abstract

Caregivers of patients diagnosed with cancer experience stress associated with their roles and responsibilities as a caregiver. These stressors contribute to psychosocial issues among this population and many caregivers experience loneliness. A caregiver’s neighborhood context and financial circumstances could be associated with loneliness. The current study had two objectives: (1) examine the associations among area deprivation index, household income, and loneliness for caregivers of patients with cancer and (2) identify potential interaction effects between area deprivation index and household income on loneliness.

Demographic data and baseline surveys for our study were derived from a larger clinical trial of caregivers of patients with cancer receiving outpatient palliative care. Participants were geocoded to determine their census block group and corresponding area deprivation index percentile. Linear models were estimated to assess associations among area deprivation index, household income, and loneliness, and models were subsequently adjusted for several demographic and caregiving context covariates.

The results showed that there was no significant association between area deprivation index and loneliness but did indicate an association between household income and loneliness: caregivers with annual household incomes less than $70,000 experienced greater loneliness on average than those with annual household incomes greater than $70,000. There was no detectable interaction effect of area deprivation index and household income on loneliness.

These results indicate that financial and income data should be considered when developing clinical practices or infrastructure to ameliorate loneliness in caregivers of patients with cancer.

## Linked entities

- **Diseases:** cancer (MONDO:0004992)

## Full-text entities

- **Diseases:** Cancer (MESH:D009369), ADI (MESH:D012892), dementia (MESH:D003704), anxiety (MESH:D001007), Alzheimer's disease (MESH:D000544), depression (MESH:D003866), distress (MESH:D012128), frailty (MESH:D000073496), toxicity (MESH:D064420), sleep disorders (MESH:D012893)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12999699/full.md

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Source: https://tomesphere.com/paper/PMC12999699