# Rare renal tumor: a case report of collecting duct carcinoma and literature review

**Authors:** Cheng Zhu, Yingfang Zhang, Zhong Tian, Tingting Yang, Guang Han, Huangyu Luo, Bo Yu, Neng Zhang, Ni Fu

PMC · DOI: 10.3389/fonc.2026.1674239 · 2026-03-05

## TL;DR

This paper reports a rare case of collecting duct carcinoma, a severe kidney cancer, and reviews existing literature to improve understanding of its diagnosis and treatment.

## Contribution

The paper contributes a new case report and a literature review on the rare collecting duct carcinoma subtype of kidney cancer.

## Key findings

- Collecting duct carcinoma is rare, aggressive, and often diagnosed at advanced stages.
- Surgery is the primary treatment, but prognosis remains poor due to late diagnosis.
- The case presented primarily showed symptoms of hematuria.

## Abstract

Collecting duct carcinoma (CDC), also known as Bellini duct carcinoma, is an extremely rare and highly aggressive subtype of renal cell carcinoma. Most patients present with metastasis at the time of diagnosis, and the prognosis for CDC patients is generally poor. Surgery is the primary treatment approach. In this article, we report a case of CDC presenting primarily with hematuria and provide a comprehensive review of the published literature concerning its diagnosis, treatment, and prognosis. The aim is to enhance understanding of this rare renal malignancy by elucidating its clinical and pathological characteristics and supplementing relevant treatment experiences.

## Linked entities

- **Diseases:** collecting duct carcinoma (MONDO:0005220), renal cell carcinoma (MONDO:0005086)

## Full-text entities

- **Diseases:** hematuria (MESH:D006417), Bellini duct carcinoma (MESH:D021441), metastasis (MESH:D009362), renal tumor (MESH:D007680), renal malignancy (MESH:D009369), CDC (MESH:D002292)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12999396/full.md

---
Source: https://tomesphere.com/paper/PMC12999396