# A case of pulmonary mucosa-associated lymphoid tissue lymphoma with plasmacytic differentiation and amyloid deposition: case report and literature review

**Authors:** Zhihui Wang, Xiaoxi Wang, Dingrong Zhong

PMC · DOI: 10.3389/fonc.2026.1718760 · 2026-03-05

## TL;DR

This paper reports a rare case of a slow-growing lung lymphoma with unusual features, aiming to increase awareness among pathologists.

## Contribution

The novelty lies in documenting a rare combination of plasmacytic differentiation and amyloid deposition in pulmonary MALT lymphoma.

## Key findings

- MALT lymphoma with plasmacytic differentiation and amyloid deposition is a rare occurrence.
- Amyloid deposition is uncommon in MALT lymphoma cases.
- This case highlights the importance of recognizing rare features in MALT lymphoma for accurate diagnosis.

## Abstract

Mucosa-associated lymphoid tissue (MALT) lymphoma is a relatively uncommon subtype of non-Hodgkin lymphoma which occurs anywhere but lymph nodes. We present a case of MALT lymphoma with plasmacytic differentiation and amyloid deposition. Although plasmacytic differentiation is shown in some cases, amyloid deposition is the rare one in the current cases we collected. Amyloidosis is often associated with some malignant diseases, but MALT is known as an indolent lymphoma. We want to report this case to raise pathologists’ cognizance on this disease.

## Linked entities

- **Diseases:** MALT lymphoma (MONDO:0007650), amyloidosis (MONDO:0019065), non-Hodgkin lymphoma (MONDO:0018908)

## Full-text entities

- **Diseases:** lymphoma (MESH:D008223), non-Hodgkin lymphoma (MESH:D008228), Amyloidosis (MESH:D000686), MALT lymphoma (MESH:D018442)

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12999391/full.md

---
Source: https://tomesphere.com/paper/PMC12999391