# Arterial thoracic outlet syndrome due to a first-rib anomaly causing brachial artery embolic occlusion: a case report

**Authors:** Nahiro Yan, Fumie Sugihara, Koichi Akutsu, Taiga Matsumoto, Tatsuo Ueda, Hidemasa Saito, Ryutaro Fujitsuna, Sayaka Shirai, Shiori Shimizu, Hiromitsu Hayashi, Shin-Ichiro Kumita

PMC · DOI: 10.1016/j.radcr.2026.02.020 · 2026-03-14

## TL;DR

A rare case of arterial thoracic outlet syndrome caused by a first-rib anomaly led to brachial artery occlusion and was diagnosed using 3D imaging.

## Contribution

Demonstrates the importance of 3D imaging in diagnosing complex thoracic outlet anomalies.

## Key findings

- 3D imaging identified focal arterial compression due to rib fusion, confirming the diagnosis.
- Routine 2D imaging may delay diagnosis in complex thoracic outlet cases.
- Bilateral first-rib anomalies were present, but only the right side caused arterial compression.

## Abstract

Arterial thoracic outlet syndrome is a rare condition caused by compression of the subclavian artery at the thoracic outlet, which often leads to delayed diagnosis and potentially severe outcomes such as upper limb necrosis. We report a case of a man in his 20s who presented with coldness in the right fingers, exacerbated by cold environments. Chest radiography revealed abnormal bone structures, and contrast-enhanced computed tomography confirmed stenosis and post-stenotic dilation of the right subclavian artery, thrombus formation, and occlusion of the brachial artery. Although bilateral first-rib anomalies were present, three-dimensional volume-rendered imaging identified focal arterial compression on the right side due to abnormal fusion of the first and second ribs, leading to a definitive diagnosis of arterial thoracic outlet syndrome. This case highlights that reliance on routine two-dimensional imaging alone may contribute to diagnostic delay, whereas selective use of three-dimensional reconstruction can provide critical anatomical insight, enabling accurate diagnosis and appropriate management in patients with complex thoracic outlet anatomy.

## Linked entities

- **Diseases:** arterial thoracic outlet syndrome (MONDO:0018164)

## Full-text entities

- **Diseases:** stenosis (MESH:D003251), first-rib anomalies (MESH:C537613), upper limb necrosis (MESH:D038062), brachial artery embolic occlusion (MESH:D001157), Arterial thoracic outlet syndrome (MESH:D013901), thrombus (MESH:D013927)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12999296/full.md

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Source: https://tomesphere.com/paper/PMC12999296