Single-stage surgical modification for neonatal aortic coarctation and ventricular septal defect: a case report
Xinmeng Yang, Pengchao Xing, Kefeng Hou, Rui Chen, Silin Pan

TL;DR
A new surgical method successfully treats a complex heart defect in newborns without using high-risk techniques.
Contribution
A modified single-stage surgical approach that avoids deep hypothermic circulatory arrest in neonates with aortic coarctation and VSD.
Findings
The modified approach achieved successful repair with a short recovery period and no complications.
Avoiding deep hypothermic circulatory arrest reduced neurological risks and CPB duration.
Excellent postoperative cardiac function was confirmed at discharge.
Abstract
Coarctation of the aorta (CoA) with a non-restrictive ventricular septal defect (VSD) is a severe congenital heart defect. Traditional single-stage repair often requires deep hypothermic circulatory arrest (DHCA), increasing surgical risk in neonates. A 1-day-old male neonate with prenatal diagnosis of CoA and VSD presented with respiratory distress. Imaging confirmed CoA with arch hypoplasia and a large VSD. He underwent a modified single-stage repair via median sternotomy. The innovative approach involved initial aortic arch reconstruction without cardiopulmonary bypass (CPB), followed by VSD closure under mild hypothermic CPB. The chest was closed primarily. Recovery was remarkable: ventilator support 23 h, intensive care unit stay 4 days, and total hospitalization 13 days. Discharge echocardiogram showed excellent cardiac function with no complications. This modified single-stage…
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
Click any figure to enlarge with its caption.
Figure 1
Figure 2
Figure 3
Figure 4
Figure 5Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsCongenital Heart Disease Studies · Aortic Disease and Treatment Approaches · Tracheal and airway disorders
