# Anterolateral Papillary Muscle Rupture After Acute Myocardial Infarction Leading to Severe Mitral Regurgitation: A Case Report

**Authors:** Zeyan Liu, Shou Zhou, Xuexiang Li, Qi Yang, Xiaodong Pan

PMC · DOI: 10.1002/ccr3.71551 · 2025-12-01

## TL;DR

A rare case of anterolateral papillary muscle rupture after a heart attack caused severe mitral regurgitation, highlighting unusual clinical signs.

## Contribution

Reports a rare case of anterolateral papillary muscle rupture after acute myocardial infarction without left main lesion.

## Key findings

- Anterolateral papillary muscle rupture is rare in acute myocardial infarction without left main lesion.
- Early 'pseudo-normalization' of ejection fraction may mislead clinical assessment.
- Severe mitral regurgitation occurred with partial valve body prolapse.

## Abstract

Due to dual blood supply, ischemic mitral anterolateral papillary muscle rupture is less common than that of posteromedial papillary muscle and is rare in acute myocardial infarction without left main lesion. “Pseudo‐normalization” phenomenon of left ventricular ejection fraction may occur in the early stage, which is inconsistent with clinical symptoms.

Mitral anterolateral papillary muscle rupture with partial valve body prolapse and severe mitral regurgitation after acute myocardial infarction (ultrasound schematic).

## Linked entities

- **Diseases:** acute myocardial infarction (MONDO:0004781)

## Full-text entities

- **Diseases:** Papillary Muscle Rupture (MESH:D012421), Acute Myocardial Infarction (MESH:D009203), ischemic (MESH:D002545), left main lesion (MESH:D003324)

## Figures

8 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12998256/full.md

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Source: https://tomesphere.com/paper/PMC12998256