# Analysis of factors influencing axial length changes in adolescents wearing corneal reshaping lenses

## TL;DR

This study identifies factors affecting eye growth in adolescents using corneal reshaping lenses to manage myopia.

## Contribution

The study reveals eye-specific factors influencing axial length changes in adolescents using orthokeratology lenses.

## Key findings

- Age and initial spherical lens value significantly predict axial length changes in both eyes.
- Duration of lens use and initial axial length also significantly influence changes.
- Factors affecting the left and right eyes differ, with age being significant only in the right eye.

## Abstract

This study aimed to identify factors influencing axial length changes in
adolescents wearing orthokeratology lenses.

A retrospective analysis was conducted on 84 adolescents (aged 9-17 yr) who
wore orthokeratology lenses at our hospital. Axial length changes were
calculated as the difference between the first and last visits. Patients
were categorized into two groups based on axial length change:
lower-than-average and higher-than-average. Data on sex, age at
orthokeratology lens initiation, family history, initial equivalent
spherical lens value, initial cylindrical lens value, initial average K
value, and initial axial length were collected. Univariate and mixed-effects
model analyses were performed to assess their influence on axial length
changes.

Age (p<0.05) and initial equivalent spherical value (p<0.05) were
significant predictors of axial length changes in both eyes and the left
eye. For the right eye, only age was a significant factor (p<0.05). The
mixed-effects model revealed that the difference between the left and right
eyes, duration of orthokeratology lens use, age, initial equivalent
spherical lens value, and initial axial length significantly influenced
axial length changes in adolescents (p<0.05).

The factors influencing axial length changes in adolescents wearing
orthokeratology lenses differ between the left and right eyes. These changes
depend on the duration of lens wear, age, initial equivalent spherical lens
value, and initial axial length. This study provides a theoretical basis for
evaluating the clinical efficacy of orthokeratology lenses in managing
myopia progression in adolescents.