Features and management of a case of melanocytoma with vitreous seeding
Carlos Augusto Ferraresi Sampaio, Gustavo Rosa Gameiro, Carolina Correa Valente, Zelia Maria Correa
Abstract
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Figure 1- —National Eye Institute
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TopicsOcular Oncology and Treatments · Glioma Diagnosis and Treatment · Brain Metastases and Treatment
A patient presented with a dark-brown tumor and melanotic vitreous cells in the amblyopic right eye (OD) (Figure A). OCT revealed a sonolucent optic disc tumor (Figure B). Differentials for this finding included metastatic cutaneous melanoma, necrotic uveal melanoma, and melanocytoma with vitreous seeding^(1^,^2)^. A vitrectomy confirmed the diagnosis of a melanocytoma with low metastatic risk (Class 1, PRAME-negative) and an excellent outcome^(1^,^3)^ (Figures C and D). Optic disc melanocytomas occasionally enlarge, causing visual loss due to spontaneous tumor necrosis or compressive neuropathy^(1^,^4)^. Malignant transformation occurs in 1%-2% of the lesions^(5)^.
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