Unwanted scenario of medical journals’ future: Artificial intelligence and medical writing
Shigeki Matsubara, Yuanyuan Liu, Haoran Mao, Renato Ambrósio Jr., Alexandre Batista da Costa Neto, Matheus Puppe Magalhães, Milton Yogi, Kaio Pereira, Aydano Pamponet Machado

Abstract
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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Taxonomy
TopicsArtificial Intelligence in Healthcare and Education
Dear Editor,
Two recent articles on generative artificial intelligence (GenAI) in academic writing warrant attention. Liu et al.’s review^(1)^ stands out, and Ambrósio et al.’s^(2)^ insights are particularly astute. While both papers highlight GenAI’s impressive capabilities, they also express concerns about its drawbacks, particularly the risk of over-reliance on it. To complement their concern, l outline a hypothetical, undesirable future scenario that GenAI might bring to academic publishing. Rather than offering prescriptive solutions, my aim is to stimulate a broader conversation about the implications of GenAI in academic writing.
The current state of GenAI use in writing can be summarized as follows:
These factors create a complex unresolved issue that stakeholders will continue to grapple with^(4)^. The challenge lies in striking a balance between genuine human writing and reliance on AI^(1^, ^4)^. Achieving a universally acceptable balance seems elusive, as opinions on the matter tend to be highly subjective. What will the future of paper writing look like? l will illustrate one possible, albeit extreme scenario that may, paradoxically, help clarify or even resolve this conundrum.
In the future, medical papers may resemble a “dictionary”, losing the element of “how it’s written”. Traditionally, we have valued both content (“what is written”) and tone (“how it is written”) in medical papers. An extreme example of the latter is seen in “human touch” (anecdotes, experiential insights, and proverbial wisdom). This touch enriches manuscripts^(5)^. However, we may need to abandon such touch or tone.
A dictionary? Nobody minds its “flat” descriptions. We do not expect a writing tone from it: accuracy and thus “what is written” matters. lf “dictionary-like papers” is difficult to imagine, consider an anatomy textbook, where most pages feature straightforward factual statements.
I anticipate that future papers will become more formulaic and dry, resembling a dictionary or an anatomy textbook. For instance, essential information may be condensed into bullet-point formats (Table 1), replacing the traditional IMRaD (Introduction, Methods, Results, and Discussion) style. Once adapted, this style may enable readers to rapidly grasp core points, much like referencing a dictionary.
A bullet-point style manuscript may require minimal writing finesse, freeing authors from concerns about tone and style. By excluding these elements, reliance on AI decreases, leaving only the content. Writing bullet points is straightforward, making AI assistance less necessary. Thus, AI reliance will naturally wane. I am not dismissing the value of IMRaD; with over 590 PubMed-indexed papers under my belt, I respect its merits, forged through the persistent efforts of many. Still, I foresee a shift. IMRaD may not be eternal.
This bullet-point style comes with a cost: the loss of individual tone and writing flair. I fervently hope Editorials, Opinions, and Letters remain the domain of human writers. In these “thought-expressing pieces”, “how it is written” holds significant weight^(5)^. If original papers lose this element, such pieces will become even more important.
Perhaps journals will resemble a “column among data books”, with thought-expressing pieces serving as columns where the role of authors as “writers” is preserved.
I expect the academic community to find solutions that balance AI’s benefits with preserving individuality in writing, rendering my concerns moot. I hope this is the case. Even in a worst-case scenario, I believe that individuality can still be expressed in subtle details. Just as high-school students in identical uniforms can express themselves through small touches, like a red lining, humans are wired to notice and appreciate these nuances.
The reference list from the paper itself. Each links out to its DOI / PubMed record.
- 1Liu Y Kong W Merve K Chat GPT applications in academic writing: a review of potential, limitations, and ethical challenges Arq Bras Oftalmol 2025883 e 2024 e 026910.5935/0004-2749.2024-0269 PMC 1299764939879415 · doi ↗ · pubmed ↗
- 2Ambrósio R Jr Costa AB Neto Magalhães MP Yogi M Pereira K Machado AP Ethical implications of using artificial intelligence to support scientific writing Arq Bras Oftalmol 2025882 e 2025-001810.5935/0004-2749.2025-0018 PMC 1299760540008723 · doi ↗ · pubmed ↗
- 3Else H Group to establish standards for AI in papers Science 202438466932612613863569910.1126/science.adp 8901 · doi ↗ · pubmed ↗
- 4França TFA Monserrat JM The artificial intelligence revolution... in unethical publishing: will AI worsen our dysfunctional publishing system?J Gen Physiol 202415611 e 2024136543937365610.1085/jgp.202413654 PMC 11461141 · doi ↗ · pubmed ↗
- 5Matsubara S Matsubara D What’s the difference between human-written manuscripts versus Chat GPT-generated manuscripts involving “human touch”?J Obstet Gynaecol Res 2025512 e 16226 e 162263991002910.1111/jog.16226 · doi ↗ · pubmed ↗
- 6Guimarães CA Structured abstracts: narrative review Acta Cir Bras 20062142632681686234910.1590/s 0102-86502006000400014 · doi ↗ · pubmed ↗
- 7ESMO Guidelines Committee Reporting standards for cancer immunotherapy: the ESMO quality checklist Ann Oncol 2020311216571661
- 8Zhang Y Le Cun Y Bengio S Domain-specific fine-tuning of large language models for hypothesis-driven writing Nat Mach lntell 202574201210
