Leukemic retinopathy
Carolina Minelli Martines, Nicole Bulgarão Maricondi de Almeida, Newton Kara-Junior
Abstract
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TopicsRetinoids in leukemia and cellular processes · Drug-Induced Ocular Toxicity · Acute Myeloid Leukemia Research
Leukemia is a systemic and heterogeneous^(1)^ hematological disease, with retinal involvement as the most common ocular manifestation^(2)^. Leukemic retinopathy (Figure 1) may arise from direct infiltration or hematologic abnormalities. These manifest as intraretinal or preretinal hemorrhages and cotton-wool spots^(2)^. Treatment resolves the retinopathy within the first 2 months^(2)^. Management should be individualized based on the patients’ underlying medical condition^(1)^. If untreated, the sequelae include choroidal neovascularization and tractional retinal detachments^(2)^.
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- 1Ghanbarnia M Sedaghat S Rasoulinejad SA. Leukemic retinopathy presenting as concurrent bilateral subhyaloid hemorrhage and subarachnoid hemorrhage in a patient with acute monocytic leukemia: a case report J Med Case Rep[Internet]2022 cited 2024 Aug 21161466 Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC 9758892/ 3652713810.1186/s 13256-022-03700-4PMC 9758892 · doi ↗ · pubmed ↗
- 2Beketova T Mordechaev E Murillo B Schlesinger MD. Leukemic retinopathy: a diagnostic clue for initial detection and prognosis of leukemia Creus[Internet]2023 cited 2024 Sep 211512 e 50587 Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC 10788118/ 10.7759/cureus.50587 PMC 1078811838222198 · doi ↗ · pubmed ↗