# Disparities in ACL Injury and Management: The Impact of Sex, Race, and Social Determinants of Health

## TL;DR

This paper reviews how sex, race, and socioeconomic factors affect ACL injury rates and outcomes, highlighting opportunities to improve equity in treatment and recovery.

## Contribution

The paper identifies modifiable factors in rehabilitation and access to care that could reduce disparities in ACL injury and recovery outcomes.

## Key findings

- Female patients have higher ACL injury rates and lower return-to-sport rates despite similar surgical outcomes.
- Racial and ethnic minorities face delayed surgery and worse outcomes due to socioeconomic and access barriers.
- Neuromuscular rehabilitation and equitable access to therapy can reduce disparities in ACL recovery.

## Abstract

Anterior cruciate ligament (ACL) injury is a common condition that significantly affects physical function and long-term knee health across diverse patient populations. Although outcomes after ACL reconstruction have improved, growing evidence demonstrates persistent disparities related to biological sex, gender, race, ethnicity, and socioeconomic factors. This review synthesizes recent literature examining how these factors influence ACL injury risk and outcomes, with the goal of identifying actionable gaps and future directions to improve equity in ACL management.

Recent studies confirm that female patients sustain ACL injuries at higher rates and experience inferior patient-reported outcomes and lower return-to-sport rates despite largely equivalent objective surgical outcomes. Recent work highlights neuromuscular and plyometric-based rehabilitation, psychological readiness, and adaptable rehabilitation environments as key modifiable contributors to these disparities. Racial and ethnic minority patients experience delayed surgical care, reduced rehabilitation utilization, and worse functional outcomes, with neighborhood-level socioeconomic deprivation and access-related barriers emerging as key modifiable contributors.

Disparities in ACL outcomes arise from the interaction of biological risk, rehabilitation-dependent recovery, and structural barriers affecting access to timely surgery and postoperative care. Rehabilitation offers a critical, modifiable opportunity to reduce these gaps by optimizing neuromuscular recovery and ensuring equitable access to supervised therapy. Future progress will require prospective, sex-, race-, or ethnicity-stratified studies, integration of area-level socioeconomic metrics, and care pathways that address delays in evaluation, surgery, and rehabilitation. Earlier implementation of neuromuscular injury-prevention programs in youth and community-based settings may further reduce downstream disparities.