# Recurrent Mental Cutaneous Metastases Secondary to Bilateral Renal Cell Carcinoma

**Authors:** Jessica L Hoffman, Chase E Green, Monica Botros, Javier Corral

PMC · DOI: 10.7759/cureus.103673 · Cureus · 2026-02-15

## TL;DR

This paper describes a rare case of kidney cancer that spread to the bladder and skin, highlighting the challenges in treating metastatic disease and the need for better therapies.

## Contribution

The paper presents a unique case of bilateral renal cell carcinoma with rare bladder and cutaneous metastases and prolonged survival.

## Key findings

- Bladder and cutaneous metastases are rare in renal cell carcinoma.
- Surgical resection alone may not prevent recurrence in cutaneous metastases.
- Metastatic disease is associated with poor prognosis despite prolonged survival.

## Abstract

Renal cell carcinoma (RCC) is a common cancer of the urinary tract that continues to increase in incidence. With advances in imaging, RCC is being detected more frequently and at earlier stages. However, metastatic disease remains a common concern, resulting in worse prognoses. Common sites of metastases include the lungs, bone, lymph nodes, liver, brain, and adrenal glands. Bladder metastases are rare, with fewer than a hundred cases reported in the literature. Cutaneous metastases are also uncommon but have been reported. The case presented is a unique account of bilateral RCC with the development of both bladder and cutaneous metastases in the setting of prolonged survival. One treatment option for cutaneous metastases is surgical resection, as described in this case. However, based on the refractory course observed in this case, surgical resection alone may be insufficient in preventing recurrence, underscoring the need for future research investigating multimodal approaches such as combination therapy with radiation or immunotherapy. This patient went on to receive hospice care, further highlighting the relationship between metastatic disease and worsening prognoses.

## Linked entities

- **Diseases:** renal cell carcinoma (MONDO:0005086), metastatic disease (MONDO:0024883)

## Full-text entities

- **Diseases:** metastatic disease (MESH:D000092182), RCC (MESH:D002292), cancer of the urinary tract (MESH:D014571), Bladder metastases (MESH:D009362)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12995578/full.md

## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12995578/full.md

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Source: https://tomesphere.com/paper/PMC12995578