# The role of indigenous knowledge and cultural dynamics in immunization uptake in Africa

**Authors:** Frankline Sevidzem Wirsiy, Clovis Nchinjoh Sangwe, Arrey Denis Ebot Ako-, Nancy Tahmo, Eugene Vernyuy Yeika, Clinton Njakoi Kwemu, Jean-Claude Kindzeka Wirsiy, Roseline Dzekem Dine

PMC · DOI: 10.11604/pamj.2025.52.168.46893 · The Pan African Medical Journal · 2025-12-17

## TL;DR

The paper argues that incorporating indigenous knowledge and cultural practices can improve vaccine uptake in Africa by building trust and addressing cultural misconceptions.

## Contribution

The novel contribution is proposing a three-pronged 'LET' framework to integrate indigenous knowledge into immunization programs.

## Key findings

- Indigenous knowledge and cultural dynamics significantly influence vaccine acceptability in African communities.
- Engaging traditional leaders and healers can enhance trust in immunization programs.
- A culturally sensitive approach improves vaccine resilience and uptake in underserved areas.

## Abstract

Despite fifty years of development in immunization programs, vaccine uptake is still inconsistent throughout many parts of Africa. As global public health experts with a background in epidemiology and control of infectious diseases, including community engagement, we think the secret to closing the gap lies in the indigenous knowledge and cultural dynamics. These factors, which have their roots in conventional systems, affect vaccine acceptability by influencing how people view health and illness. This viewpoint emphasizes how indigenous customs, cultural values, and contemporary vaccination methods interact. Using cultural rites, the roles of traditional rulers, traditional healers, and community gatekeepers as examples, we suggest incorporating these dynamics into standard immunization frameworks. This culturally sensitive technique will promote equal vaccine uptake among Africa's diverse communities by developing trust and bolstering vaccination resilience. Cultural and indigenous practices are key to understanding barriers to immunization uptake, especially in rural and underserved communities. This school of thought addresses how leveraging indigenous knowledge can strengthen routine immunization programs and improve resilience against vaccine hesitancy rooted in cultural misconceptions. To effectively incorporate indigenous knowledge and cultural dynamics into immunization frameworks, we propose a three-pronged approach dubbed, the ´LET´ perspective i.e. L= leverage cultural events, E=engage traditional elders and healers, T=train community healthcare workers.

## Full-text entities

- **Diseases:** infectious diseases (MESH:D003141), polio (MESH:D011051), COVID-19 (MESH:D000086382), malaria (MESH:D008288)

## Full text

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## References

26 references — full list in the complete paper: https://tomesphere.com/paper/PMC12995558/full.md

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Source: https://tomesphere.com/paper/PMC12995558