# Bioinformatics analysis of the KEA gene family in rice

**Authors:** Zhenyu Zhang, Shu Dang

PMC · DOI: 10.1515/biol-2025-1230 · Open Life Sciences · 2026-03-18

## TL;DR

This paper identifies and analyzes the KEA gene family in rice, providing insights into their potential roles in growth and stress resistance.

## Contribution

The study is the first to analyze the KEA gene family in rice using bioinformatics methods.

## Key findings

- Eight KEA family genes were identified in rice with specific chromosomal localization.
- The genes show distinct domains and tissue-specific expression patterns.
- The findings provide a foundation for understanding the function of KEA genes in rice.

## Abstract

KEA (K+/H+ reverse transporter, K+ efflux antiporter) gene family belongs to the CPA2 reverse transporter superfamily gene, which plays an important role in regulating plant growth and development and stress resistance by maintaining intracellular PH balance and K+ concentration. The studies on the function of KEA gene in plants mainly focus on Arabidopsis thaliana, and the studies on the function of KEA gene family in rice have not been reported. In this study, the evolutionary tree analysis, chromosome localization, protein physicochemical properties and tissue expression of rice KEA gene family were analyzed by bioinformatics methods. Eight KEA family genes were identified in rice, some localized on specific chromosomes, with particular domains and different expression patterns. These results provided references for the research and analysis of the function of rice KEA gene family.

## Linked entities

- **Species:** Oryza sativa (taxon 4530), Arabidopsis thaliana (taxon 3702)

## Full-text entities

- **Chemicals:** K+ (MESH:D011188)
- **Species:** Arabidopsis thaliana (mouse-ear cress, species) [taxon 3702], Oryza sativa (Asian cultivated rice, species) [taxon 4530]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12995388/full.md

## References

30 references — full list in the complete paper: https://tomesphere.com/paper/PMC12995388/full.md

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Source: https://tomesphere.com/paper/PMC12995388