# Sequenced psychotherapy improves evidence-based trauma-focused psychotherapy initiation and retention in a national sample of veterans

**Authors:** William R. Wolfe, Anna Staudenmeyer, Marylene Cloitre, Asale Hubbard, Martha Schmitz, Brian Mohlenhoff, Shira Maguen, Thomas C. Neylan

PMC · DOI: 10.1016/j.psychres.2025.116612 · Psychiatry research · 2026-03-17

## TL;DR

Adding non-trauma therapy before trauma-focused care helps more veterans start and complete PTSD treatment, especially for some minority and high-risk groups.

## Contribution

This study shows sequenced psychotherapy improves initiation and retention in trauma-focused PTSD treatments for veterans.

## Key findings

- Sequenced psychotherapy increased CPT and PE initiation by 0.4-6.8% across groups.
- Retention in CPT and PE improved by 8-8.7% after sequenced therapy.
- Hispanic White veterans with heavy drinking had a 21.7% increase in CPT retention after group sequenced therapy.

## Abstract

Posttraumatic stress disorder (PTSD) is a disabling condition costing the Veterans Administration (VA) $5 billion annually in disability compensation. Despite system-wide dissemination of Cognitive Processing Therapy (CPT) and Prolonged Exposure (PE) since 2007, only a small minority of veterans complete these treatments. We investigated the impact of sequenced treatment on initiation of and retention in CPT and PE across self-reported race and ethnicity, as well as recent heavy drinking and suicidal ideation (SI).

VA administrative data were used to assess the impact of sequenced psychotherapy (SP), in which ≥ 8 sessions of non-trauma-focused individual (SPI) or group (SPG) psychotherapy was delivered before trauma-focused care, on initiation and retention in CPT and PE over two years from PTSD treatment initiation. Results were analyzed by self-reported race and ethnicity, heavy drinking (AUDIT-C ≥6), and SI (PHQ9 Q9>1).

Nationwide, 12.9 % of veterans who entered care for PTSD between 10/1/2014 and 11/30/2020 (n = 490,097) initiated VA-disseminated evidence-based treatment within 21 months (9.5 % CPT, 3.4 % PE). Among those, treatment retention (≥ 8 sessions) was 46.4 % and 42.3 %, respectively. SPI and SPG were associated with 0.4-6.8 % increases in CPT and PE initiation across racial/ethnic and risk groups. SPI was associated with increased CPT and PE retention of 8.0 % and 8.2 %; for SPG, retention increases were 3.4 % and 8.7 %. Strikingly, Hispanic White veterans with heavy drinking had 21.7 % increased CPT retention following SPG.

Sequential individual and group psychotherapy may improve initiation and completion of CPT and PE, particularly for certain minoritized and high-risk groups.

## Linked entities

- **Diseases:** Posttraumatic stress disorder (MONDO:0005146), PTSD (MONDO:0005146)

## Full-text entities

- **Diseases:** trauma (MESH:D014947), SI (MESH:D001072), PTSD (MESH:D013313)

## Full text

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## References

63 references — full list in the complete paper: https://tomesphere.com/paper/PMC12994157/full.md

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Source: https://tomesphere.com/paper/PMC12994157