# Obstructive shock caused by infection of a mediastinal tumor: a case report and literature review

**Authors:** Wenxin Wang, Luping Cheng, Xia Hu, Hong Wan, Chuanliang Pan

PMC · DOI: 10.3389/fmed.2026.1726710 · Frontiers in Medicine · 2026-03-03

## TL;DR

A rare case of obstructive shock caused by a mediastinal tumor infection is reported, highlighting the importance of early diagnosis and treatment.

## Contribution

This case report adds to the limited literature on obstructive shock caused by mediastinal tumor infection and emphasizes diagnostic approaches.

## Key findings

- Obstructive shock can result from infection of an unresectable mediastinal tumor.
- CT scans and PICCO monitoring are valuable for early diagnosis.
- Anti-infective therapy and symptomatic management led to tumor size reduction.

## Abstract

Mediastinal tumor are a category of neoplasms that arise in the central region of the thoracic cavity. The clinical manifestations of this condition are diverse and have the potential to precipitate a range of severe complications, including obstructive shock. A comprehensive understanding of the etiology of mediastinal tumor is imperative for the timely recognition and intervention.

The present case study focuses on a 38-year-old female patient who exhibited symptoms of chest tightness and dyspnea, devoid of any discernible precipitating factors. A chest CT scan revealed a mediastinal mass, which the patient initially disregarded. As symptoms worsened, her dyspnea significantly intensified, prompting presentation to the Huaxi Emergency Department. The mediastinal tumor was assessed as unresectable and was compressing the heart and major vessels, exacerbating the patient’s symptoms. Preliminary diagnostic investigations confirmed the presence of obstructive shock, the etiology of which was infection of the mediastinal tumor. Following the administration of anti-infective therapy, the implementation of symptomatic management, and the undertaking of appropriate monitoring, X-ray and CT scans demonstrated a reduction in tumor size.

Obstructive shock caused by mediastinal tumor infection is relatively rare. This case review demonstrates that clinical CT scans, continuous cardiac output monitoring via pulse-wave-derived cardiac output catheter (PICCO), and assessment of clinical laboratory indicators hold significant value for early diagnosis in patients.

## Linked entities

- **Diseases:** mediastinal tumor (MONDO:0005843)

## Full-text entities

- **Diseases:** mediastinal mass (MESH:D008477), dyspnea (MESH:D004417), infection (MESH:D007239), Mediastinal tumor (MESH:D008479), neoplasms (MESH:D009369), Obstructive shock (MESH:D012769), chest tightness (MESH:D002637)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12993886/full.md

## References

21 references — full list in the complete paper: https://tomesphere.com/paper/PMC12993886/full.md

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Source: https://tomesphere.com/paper/PMC12993886