# Mechanistic insights into sonication-assisted cold plasma treatments for improved microbial decontamination and quality maintenance in perishable foods

**Authors:** Vinay Kumar Pandey, Pinku Chandra Nath, Shailendra Thapliyal, Ayaz Mukarram Shaikh

PMC · DOI: 10.1016/j.ultsonch.2026.107807 · Ultrasonics Sonochemistry · 2026-03-03

## TL;DR

This review explores how combining sonication with cold plasma improves food preservation by killing microbes and maintaining quality more efficiently.

## Contribution

The paper provides a mechanistic understanding of sonication-assisted cold plasma and its advantages over standalone methods in food preservation.

## Key findings

- SACP enhances microbial inactivation and extends shelf life with lower energy and time.
- The technology supports enzyme inactivation and bioactive retention in various food types.
- SACP shows potential for application in fruits, vegetables, dairy, and liquid foods.

## Abstract

Food preservation technologies are advancing towards the production of safe, minimally processed, and nutritious food products. Cold plasma (CP) is an emerging non-thermal technology that has received considerable attention for its potential application in decontaminating food from pathogenic and spoilage microorganisms with minimal damage to quality. Sonication, another acoustic cavitation-based technique, also provides similar synergistic advantages, such as mass transfer enhancement and disintegration of microbial membranes with enhanced exposure to reactive species. Sonication-assisted cold plasma (SACP), a combination of sonication and cold plasma, is a promising advancement in the preservation of food by enhancing the effects of microbial inactivation and shelf-life extension at lower energy input and treatment time. As well as its application for enzyme inactivation, bioactive retention, and packaging decontamination, the literature that is now accessible provides support for its potential use in fruits, vegetables, dairy products, and liquid foods. This review evaluates the fundamental concepts of sonication-assisted plasma activity. Additionally, the comparative advantages of this technology in comparison to stand-alone technologies are discussed, and the practical uses of this technology in food processing are highlighted.

## Full-text entities

- **Diseases:** SACP (MESH:D000067390), wounds (MESH:D014947), fungal (MESH:D009181), allergy (MESH:D004342), discoloration (MESH:D014075)
- **Chemicals:** starch (MESH:D013213), tryptophan (MESH:D014364), benzoates (MESH:D001565), free radicals (MESH:D005609), peroxynitrite (MESH:D030421), Lipid (MESH:D008055), nitrites (MESH:D009573), pectin (MESH:D010368), Carotenoids (MESH:D002338), nitric oxide (MESH:D009569), phenolic acids (MESH:C017616), sulphate (MESH:D013431), free amino acids (-), disulfide (MESH:D004220), oxygen (MESH:D010100), O3 (MESH:D010126), sulphites (MESH:D013447), anthocyanin (MESH:D000872), Vitamin C (MESH:D001205), quinones (MESH:D011809), polyphenol (MESH:D059808), ATP (MESH:D000255), flavonoids (MESH:D005419), tyrosine (MESH:D014443), nitrogen (MESH:D009584), essential oils (MESH:D009822), chlorophyll (MESH:D002734), sugars (MESH:D000073893), water (MESH:D014867), lycopene (MESH:D000077276), Hydroxyl (MESH:D017665), ROS (MESH:D017382), RNS (MESH:D026361), Ester (MESH:D004952), singlet oxygen (MESH:D026082), CP (MESH:D058626), nitrogen dioxide (MESH:D009585), cysteine (MESH:D003545), OH (MESH:C031356), amino acid (MESH:D000596), H2O2 (MESH:D006861)
- **Species:** Listeria monocytogenes (species) [taxon 1639], Homo sapiens (human, species) [taxon 9606], Fungi (kingdom) [taxon 4751], Vibrio parahaemolyticus (species) [taxon 670], Salmonella (genus) [taxon 590], Staphylococcus aureus (species) [taxon 1280], Solanum tuberosum (potatoes, species) [taxon 4113], Bacteria Latreille et al. 1825 (Bacteria stick insect, genus) [taxon 629395], Saccharomyces cerevisiae (baker's yeast, species) [taxon 4932], Malus domestica (apple, species) [taxon 3750], Daucus carota (carrot, species) [taxon 4039], Escherichia coli O157:H7 (no rank) [taxon 83334], Escherichia coli (E. coli, species) [taxon 562], Cucumis sativus (cucumber, species) [taxon 3659], Spinacia oleracea (spinach, species) [taxon 3562], Solanum lycopersicum (tomato, species) [taxon 4081]

## Full text

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## Figures

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## References

136 references — full list in the complete paper: https://tomesphere.com/paper/PMC12993394/full.md

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Source: https://tomesphere.com/paper/PMC12993394