# Harnessing oncogenic signaling to enhance oncolytic virotherapy: Lessons from EPAC-encoding vaccinia virus

**Authors:** Stephen Boulton, Siddharth Singh, John C. Bell

PMC · DOI: 10.1016/j.omton.2026.201165 · Molecular Therapy Oncology · 2026-03-10

## Full-text entities

- **Genes:** RAPGEF3 (Rap guanine nucleotide exchange factor 3) [NCBI Gene 10411] {aka CAMP-GEFI, EPAC, EPAC1, HSU79275, bcm910}
- **Species:** Orthopoxvirus vaccinia (species) [taxon 10245]

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## References

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Source: https://tomesphere.com/paper/PMC12993383