# Renal sinus leiomyoma mimicking papillary renal cell carcinoma: A case report

**Authors:** Shinichi Ozaki, Takahiro Yamamoto, Sou Unten, Ryotaro Shimizu, Nobuo Yokoyama, Ayumi Asai, Akiko Narita, Hiroaki Okada, Masashi Shimohira, Haruka Kurosu, Takanori Ito, Kojiro Suzuki

PMC · DOI: 10.1016/j.radcr.2026.01.092 · Radiology Case Reports · 2026-03-05

## TL;DR

A rare case of a benign kidney tumor in a young woman was initially mistaken for a more serious cancer due to similar imaging features.

## Contribution

This case report highlights the diagnostic challenge of renal sinus leiomyoma mimicking papillary renal cell carcinoma.

## Key findings

- The tumor was a 4 cm, well-circumscribed mass in the renal sinus with imaging features similar to papillary renal cell carcinoma.
- Pathological examination confirmed the diagnosis of renal leiomyoma after surgical removal due to biopsy difficulty.
- Imaging alone could not definitively distinguish the benign tumor from malignant papillary renal cell carcinoma.

## Abstract

Renal leiomyomas are rare benign tumors that predominantly affect women in their 40s and 50s. Here, we report a case of renal leiomyoma originating from the renal sinus of a woman in her 30s. The lesion was incidentally discovered on abdominal magnetic resonance imaging as a 4 cm, well circumscribed mass with smooth margins located in the right renal sinus. Dynamic contrast-enhanced computed tomography (CT) revealed homogenous and progressive enhancement, while T2-weighted magnetic resonance imaging (MRI) demonstrated uniformly low signal. Although imaging findings suggested a renal sinus tumor, papillary renal carcinoma could not be definitively excluded by imaging. Due to the difficulty in performing computed tomography-guided biopsy, a nephrectomy was undertaken. Pathological examination confirmed the diagnosis of a renal leiomyoma originating from the renal sinus.

## Linked entities

- **Diseases:** papillary renal cell carcinoma (MONDO:0017884), renal leiomyoma (MONDO:0006053)

## Full-text entities

- **Diseases:** Renal leiomyomas (MESH:D007889), renal sinus tumor (MESH:D007680), benign tumors (MESH:D009369), papillary renal carcinoma (MESH:D002292)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12993015/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC12993015/full.md

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Source: https://tomesphere.com/paper/PMC12993015