# Paradoxical Fat Embolism Syndrome During Total Hip Arthroplasty Without a Patent Foramen Ovale: A Case Report With Transesophageal Echocardiographic Findings

**Authors:** Tokimitsu Hibino, Yusuke Okui, Takuya Fujimoto, Yoshie Toba

PMC · DOI: 10.7759/cureus.103556 · Cureus · 2026-02-13

## TL;DR

A patient developed a rare fat embolism during hip surgery, causing severe complications despite no prior heart condition.

## Contribution

This case report provides novel TEE documentation of paradoxical embolism during THA without patent foramen ovale.

## Key findings

- TEE confirmed microemboli in all cardiac chambers during THA.
- Patient suffered cerebral infarction and permanent neurological damage.
- Intraoperative imaging highlights the need for rapid diagnosis and pressure control.

## Abstract

Fat embolism syndrome (FES) is a severe orthopedic complication leading to respiratory failure and neurological impairment. While bone marrow or fat entry into venous circulation is common during total hip arthroplasty (THA), cardiac arrest rarely results.

An 82-year-old woman developed pulseless electrical activity (PEA) during elective THA. During femoral reaming, a sudden decline in peripheral oxygen saturation (SpO2: 100% to 89%) and end-tidal carbon dioxide (EtCO2: 28 to 12 mmHg) was observed, followed by precipitous circulatory collapse. Transesophageal echocardiography (TEE) captured real-time video of numerous microemboli in all cardiac chambers, confirming pulmonary and paradoxical embolism. Despite successful resuscitation and surgical termination, TEE showed persistent embolic flow from the inferior vena cava (IVC). Postoperatively, the patient remained unconscious due to extensive cerebral infarction, resulting in permanent neurological sequelae.

Fat embolism during THA can be fatal. This case, documented via intraoperative imaging, highlights the need for rapid point-of-care diagnosis and proactive surgical techniques to minimize intramedullary pressure.

## Linked entities

- **Diseases:** respiratory failure (MONDO:0021113), cerebral infarction (MONDO:0002679)

## Full-text entities

- **Diseases:** cerebral infarction (MESH:D002544), cardiac arrest (MESH:D006323), neurological impairment (MESH:D009422), Paradoxical (MESH:D019320), circulatory collapse (MESH:D012769), FES (MESH:D004620), orthopedic complication (MESH:D009140), respiratory failure (MESH:D012131), embolic (MESH:D004617)
- **Chemicals:** oxygen (MESH:D010100), carbon dioxide (MESH:D002245)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12992149/full.md

## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC12992149/full.md

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Source: https://tomesphere.com/paper/PMC12992149