# Autologous fat grafting in a case of Parry-Romberg syndrome: a case report

## TL;DR

A young woman with Parry-Romberg syndrome underwent autologous fat grafting to restore facial symmetry, showing it can be a safe and effective treatment.

## Contribution

This case report demonstrates the successful use of autologous fat grafting in treating facial atrophy caused by Parry-Romberg syndrome.

## Key findings

- Autologous fat grafting successfully restored facial symmetry in a patient with Parry-Romberg syndrome.
- The procedure was found to be safe and effective over a ten-year period of facial atrophy.
- The case supports autologous fat grafting as a viable treatment option for managing PRS-related facial asymmetry.

## Abstract

Progressive hemifacial atrophy, also known as Parry-Romberg syndrome (PRS), is an uncommon condition that causes slow and progressive unilateral soft-tissue atrophy of the face. This atrophy affects the skin and subcutaneous tissue, including fat and muscle, and in some cases, may also involve the underlying bone and muscle. The exact cause of this syndrome is unknown, but several possible factors have been suggested. These include genetic predisposition, autoimmune responses, and infections or trauma. We report a case of a young female who presented with an asymptomatic one-sided atrophy of the face for the last ten years. This case highlights autologous fat grafting as a safe and effective option for restoring facial symmetry in PRS.