# ‘The good idea’: a commentary on a decade of barbed sutures in cesarean surgery

**Authors:** Maria Grazia Centurioni, Fabio Barra, Francesca Olcese, Claudio Gustavino, Simone Ferrero, Franco Alessandri

PMC · DOI: 10.1080/07853890.2026.2643495 · Annals of Medicine · 2026-03-12

## TL;DR

This paper reviews how cesarean surgical techniques, especially barbed sutures, may affect long-term uterine healing and scar quality.

## Contribution

The paper highlights the emerging role of barbed sutures in influencing uterine scar remodeling and calls for rigorous studies to confirm their clinical benefits.

## Key findings

- Barbed sutures may improve uterine scar healing by preserving perfusion and tissue alignment.
- Double-layer barbed closure is associated with thicker residual myometrial thickness and fewer niches.
- More research is needed to confirm the long-term benefits of barbed sutures in cesarean surgery.

## Abstract

Minimalist cesarean techniques have delivered clear perioperative benefits, including shorter procedures, reduced tissue dissection, and reproducibility across diverse settings. As cesarean rates rise, however, an important blind spot has emergedhow the uterine scar evolves over months and years.

To provide a narrative synthesis and methodological perspective on uterine scar healing after cesarean delivery, with particular attention to surgical determinants of lower uterine segment integrity and the emerging role of barbed sutures.

Post-cesarean niches and reduced residual myometrial thickness (RMT) are increasingly recognized as clinically relevant findings associated with abnormal bleeding, pelvic pain, subfertility, and difficult repeat surgery. Recently standardized ultrasonographic definitions allow these features to be measured reproducibly and compared across centers. Although evidence remains limited and heterogeneous, surgical factors influencing perfusion, tissue alignment, and tension distribution – shaped in part by suture material and closure technique – appear plausibly linked to long-term scar remodeling. Barbed sutures have gained interest because their knotless design distributes tension evenly and may help preserve perfusion and uniform coaptation. Comparative studies have reported associations between double-layer barbed closure and favorable imaging surrogates, such as thicker RMT and fewer or smaller niches, without apparent compromise in operative safety or efficiency. Evidence regarding subsequent pregnancy outcomes remains preliminary.

Current signals regarding barbed sutures should be interpreted cautiously and underscore the need for methodologically rigorous investigations centered on uterine healing rather than operative speed alone. Future studies should incorporate standardized transvaginal ultrasound within one to two years after delivery, harmonized reporting of niche morphology and RMT, blinded image assessment, and predefined consideration of center and surgeon effects. Within this framework, double-layer barbed closure represents a plausible but provisional option whose clinical value requires confirmation through adequately powered multicenter research.

Uterine scar quality is an increasingly relevant clinical endpoint, as reduced residual myometrial thickness (RMT) and post-cesarean niches are consistently associated with abnormal uterine bleeding, pelvic pain, subfertility, and technical difficulty at repeat surgery.Uterine closure is not a neutral surgical step: the method and material of closure, through their effects on perfusion preservation, tissue alignment, and tension distribution, may influence long-term scar remodeling.Double-layer barbed uterine closure has been associated with more favorable imaging surrogates of healing, including thicker RMT and fewer or smaller niches; very preliminary, hypothesis-generating data suggest a possible association with greater third-trimester low uterine segment (LUS) thickness in subsequent pregnancies.The current evidence base remains limited and exploratory, highlighting the need for independent, standardized, multicenter studies incorporating post-cesarean ultrasound follow-up and harmonized reporting of niche morphology and RMT before any clinical implications can be drawn.

Uterine scar quality is an increasingly relevant clinical endpoint, as reduced residual myometrial thickness (RMT) and post-cesarean niches are consistently associated with abnormal uterine bleeding, pelvic pain, subfertility, and technical difficulty at repeat surgery.

Uterine closure is not a neutral surgical step: the method and material of closure, through their effects on perfusion preservation, tissue alignment, and tension distribution, may influence long-term scar remodeling.

Double-layer barbed uterine closure has been associated with more favorable imaging surrogates of healing, including thicker RMT and fewer or smaller niches; very preliminary, hypothesis-generating data suggest a possible association with greater third-trimester low uterine segment (LUS) thickness in subsequent pregnancies.

The current evidence base remains limited and exploratory, highlighting the need for independent, standardized, multicenter studies incorporating post-cesarean ultrasound follow-up and harmonized reporting of niche morphology and RMT before any clinical implications can be drawn.

## Full-text entities

- **Diseases:** bleeding (MESH:D006470), subfertility (MESH:D007246), pelvic pain (MESH:D017699)

## Full text

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## Figures

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## References

34 references — full list in the complete paper: https://tomesphere.com/paper/PMC12990264/full.md

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Source: https://tomesphere.com/paper/PMC12990264