# RETRACTION: A Randomized, Participant‐ and Evaluator‐Blinded, Matched‐Pair, Prospective Study Comparing the Safety and Efficacy Between Polycaprolactone and Polynucleotide Fillers in the Correction of Crow's Feet

## TL;DR

A study comparing two types of dermal fillers for crow's feet was retracted due to a misidentification of the filler material used.

## Contribution

The retraction highlights the importance of accurate material identification in clinical studies involving dermal fillers.

## Key findings

- The dermal filler DLMRO1 was misidentified as containing pegylated PCL when it actually contains pure PCL.
- The misidentification affects the study's conclusions about safety and efficacy due to differing properties of the materials.
- The retraction was agreed upon by the authors and the journal to maintain scientific integrity.

## Abstract

RETRACTION:
ChoiS. Y.
,
KohY. G.
,
YooK. H.
,
HanH. S.
,
SeokJ.
, and
KimB. J.
, “A Randomized, Participant‐ and Evaluator‐Blinded, Matched‐Pair, Prospective Study Comparing the Safety and Efficacy Between Polycaprolactone and Polynucleotide Fillers in the Correction of Crow's Feet,” Journal of Cosmetic Dermatology
24, no. 1 (2025): e16576, 10.1111/jocd.16576.39313949
PMC11754925

The above article, published online on 23 September 2024 in Wiley Online Library (wileyonlinelibrary.com) has been retracted by agreement between the authors; the journal Editor‐in‐Chief, Michael H Gold; and Wiley Periodicals, LLC. The retraction has been agreed following the authors' request. The authors informed the journal that a misidentification occurred regarding the dermal filler used in the clinical study. Specifically, the product DLMRO1 dermal filler was misidentified as containing pegylated polycaprolactone (PCL), whereas it is composed solely of pure PCL filler. Because pure PCL and pegylated PCL are distinct materials with different biocompatibility, viscosity, and biodegradation profiles, the misidentification significantly affects the reported methods and undermines the reliability of the study's findings. Accordingly, the article has been retracted.