# Acute postoperative complications after scleral fixation of Akreos AO60 intraocular lens

**Authors:** Piergiacomo Grassi, Panagiotis Tsoutsanis, Robert Henderson

PMC · DOI: 10.1093/jscr/rjag159 · Journal of Surgical Case Reports · 2026-03-16

## TL;DR

This paper reports three cases of serious eye infections and inflammation after a specific type of intraocular lens surgery using Gore-Tex sutures.

## Contribution

The paper is the first to describe postoperative exogenous endophthalmitis and TASS with this surgical technique.

## Key findings

- Three patients developed endophthalmitis or TASS after scleral fixation of Akreos IOLs.
- Large corneal wounds increased the risk of complications.
- Immediate treatment was crucial for managing these complications.

## Abstract

We report three cases of postoperative exogenous endophthalmitis and toxic anterior segment syndrome (TASS) following vitrectomy for dislocated intraocular or crystalline lenses and scleral fixation of an Akreos intraocular lens (IOL) with Gore-Tex sutures. To our knowledge, postoperative exogenous endophthalmitis and TASS have not been previously described with this technique. A 67-, 56-, and 36-year-old underwent pars plana vitrectomy, lens removal or vitreolensectomy, and Akreos IOL scleral fixation. Three days later, cases 1 and 3 required vitreous biopsy and intravitreal Vancomycin/Amikacin for culture-positive endophthalmitis (Staphylococcus epidermidis and Streptococcus pneumoniae). Case 2 underwent removal of a dislocated fluocinolone implant, biopsy, and intravitreal antibiotics; negative cultures supported a diagnosis of TASS. Scleral-fixated IOLs carry risks of endophthalmitis and TASS. Large corneal wounds increase risk; meticulous wound construction is essential. Akreos IOLs do not prevent anterior migration of steroid implants. Immediate management is crucial.

## Linked entities

- **Chemicals:** Vancomycin (PubChem CID 14969), Amikacin (PubChem CID 37768)
- **Diseases:** endophthalmitis (MONDO:0016047)

## Full-text entities

- **Diseases:** endophthalmitis (MESH:D009877), corneal wounds (MESH:D014947), TASS (MESH:C537775)
- **Chemicals:** Vancomycin (MESH:D014640), fluocinolone (MESH:C035394), steroid (MESH:D013256), Amikacin (MESH:D000583), AO60 (-)
- **Species:** Streptococcus pneumoniae (species) [taxon 1313], Staphylococcus epidermidis (species) [taxon 1282]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12989712/full.md

## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC12989712/full.md

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Source: https://tomesphere.com/paper/PMC12989712