# Septic Thrombophlebitis of the Portal Vein: A Case Report

**Authors:** Megana Ballal, Eyong J Ly

PMC · DOI: 10.7759/cureus.103559 · Cureus · 2026-02-13

## TL;DR

This paper presents a case of a 53-year-old woman with septic portal vein thrombosis, emphasizing the challenges in diagnosing and treating this rare condition.

## Contribution

The novelty lies in the detailed clinical presentation and management of a rare complication of intra-abdominal infection.

## Key findings

- The patient presented with fever and abdominal pain, leading to the diagnosis of portal vein thrombosis.
- Antibiotics and anticoagulation were used in treatment, reflecting standard approaches for pylephlebitis.

## Abstract

Pylephlebitis, a septic thrombophlebitis of the portal vein, typically arises as a complication of intra-abdominal infection. We report the case of a 53-year-old woman whose presenting symptoms included fever and abdominal pain. Imaging revealed portal vein thrombosis. An evaluation was performed to identify a potential underlying infectious source. She was treated with antibiotics and anticoagulation. This case highlights the diagnostic and therapeutic complexities in the evaluation and management of pylephlebitis.

## Linked entities

- **Diseases:** portal vein thrombosis (MONDO:0001339)

## Full-text entities

- **Diseases:** fever (MESH:D005334), intra-abdominal infection (MESH:D059413), Septic (MESH:D001170), abdominal pain (MESH:D015746), portal vein thrombosis (MESH:D012170), Thrombophlebitis (MESH:D013924)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12989465/full.md

## References

8 references — full list in the complete paper: https://tomesphere.com/paper/PMC12989465/full.md

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Source: https://tomesphere.com/paper/PMC12989465