# Massive Recurrent Parotid Carcinoma in a 90-Year-Old Patient: A Case Report and Review of Management Strategies

**Authors:** Younes Banana, Ayman El Mahjoubi, Achraf Sbai, Drissia Benfadil, Azzedine Lachkar

PMC · DOI: 10.7759/cureus.103561 · Cureus · 2026-02-13

## TL;DR

This paper presents a rare case of a 90-year-old man with a malignant salivary gland tumor that developed from a long-standing benign tumor, highlighting the challenges in diagnosis and treatment.

## Contribution

The paper adds to the literature by emphasizing the diagnostic and management challenges of this rare tumor in elderly patients.

## Key findings

- The patient had a long history of recurrent pleomorphic adenoma that transformed into a malignant tumor.
- The case demonstrates the diagnostic complexity and clinical features of carcinoma ex pleomorphic adenoma.
- Management strategies for elderly patients with this condition are discussed.

## Abstract

Carcinoma ex pleomorphic adenoma is a rare malignant salivary gland tumor arising from the malignant transformation of a pre-existing pleomorphic adenoma and is associated with significant diagnostic and therapeutic challenges. We report the case of a 90-year-old male with a long-standing history of recurrent pleomorphic adenoma of the parotid gland, who presented with a rapidly enlarging parotid mass associated with facial nerve involvement and parapharyngeal extension. Histopathological examination confirmed the diagnosis of epithelial-myoepithelial carcinoma ex pleomorphic adenoma. This case highlights the clinical presentation, radiological findings, and histopathological features of this uncommon malignancy and adds to the existing literature by emphasizing the diagnostic complexity and management considerations of carcinoma ex pleomorphic adenoma in elderly patients.

## Linked entities

- **Diseases:** carcinoma ex pleomorphic adenoma (MONDO:0002472), pleomorphic adenoma (MONDO:0008401)

## Full-text entities

- **Diseases:** Parotid Carcinoma (MESH:D010307), Carcinoma ex pleomorphic adenoma (MESH:D008949), epithelial-myoepithelial carcinoma (MESH:D009375), salivary gland tumor (MESH:D012468), gland (MESH:D000307), malignancy (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12989462/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12989462/full.md

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Source: https://tomesphere.com/paper/PMC12989462