# Evolving care pathways for women with migraine in Italy: results from a national survey

**Authors:** Gianni Allais, Piero Barbanti, Mario Cepparulo, Sabina Cevoli, Cinzia Finocchi, Fabio Frediani, Nicoletta Orthmann, Paola Di Fiore

PMC · DOI: 10.3389/fneur.2026.1755791 · Frontiers in Neurology · 2026-03-02

## TL;DR

This study identifies gaps in migraine care for women in Italy and proposes expert-driven pathways to improve treatment across different life stages.

## Contribution

The paper introduces tailored care pathways for women with migraine, emphasizing multidisciplinary collaboration and life-stage-specific strategies.

## Key findings

- Diagnostic delays and fragmented care are common for women with migraine in Italy.
- Neurologists are central in managing migraine care from adolescence onward, working with other specialists.
- Key strategies include multidisciplinary collaboration, training, and awareness initiatives.

## Abstract

Migraine predominantly affects women with prolonged and more severe episodes that severely compromise their quality of life. Despite its burden, diagnostic-therapeutic pathways specifically designed for women are currently lacking, and care for women with migraine remains fragmented. By expanding the results obtained from a recent Delphi consensus study, we aim to identify key unmet needs and propose expert-driven recommendations to address female-specific migraine care in Italy.

We conducted a national survey in which the items used in the previous Delphi study were administered to a broader cohort of Italian healthcare professionals (HCPs). The survey was administered to 125 HCPs; of those, 92% were neurologists.

Diagnostic delays, insufficient multidisciplinary collaboration, and heterogeneous care emerged for women with migraine across Italy. Respondents endorsed parental awareness and socio-behavioral approaches for pediatric patients, careful evaluation of thrombotic risk for contraceptive choice, systematic assessment of migraine history and new-onset migraine during pregnancy and breastfeeding, and appropriate selection of hormone replacement therapy during menopause. Close monitoring of migraine symptoms is encouraged in oncological patients and women undergoing assisted reproduction, although evidence and guidelines for these patient subsets are currently lacking. Across all settings, the neurologist emerged as the central medical reference figure from adolescence onward, working in close collaboration with gynecologists, pediatricians, and oncologists as appropriate. Strengthening continuity of care, enhancing multidisciplinary collaboration, expanding professional training, and promoting awareness initiatives are considered the key strategies to optimize migraine care in women.

Based on the respondents' answers, we propose practical frameworks that outline migraine care pathways tailored to specific female life stages and health conditions. Efforts should prioritize the design of targeted studies to overcome the identified evidence gaps and pave the way for more structured models.

## Linked entities

- **Diseases:** migraine (MONDO:0005277)

## Full-text entities

- **Diseases:** thrombotic (MESH:D013927), Migraine (MESH:D008881)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12989344/full.md

## References

64 references — full list in the complete paper: https://tomesphere.com/paper/PMC12989344/full.md

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Source: https://tomesphere.com/paper/PMC12989344