# Impact of Combined Additional Resections on the Surgical Outcomes of Robot‐Assisted Resection of Thymic Epithelial Tumors

**Authors:** Benedikt Niedermaier, Nabil Khan, Florian Eichhorn, Maria Zehentmeier, Heidrun Grosch, Raffaella Griffo, Alessio Campisi, Antonia Margineanu, Michael Allgäuer, Petros Christopoulos, Michael Thomas, Hauke Winter, Martin E. Eichhorn

PMC · DOI: 10.1002/jso.70162 · Journal of Surgical Oncology · 2025-12-18

## TL;DR

This study examines the effectiveness and safety of robot-assisted surgery for thymic tumors, focusing on additional resections in advanced cases.

## Contribution

The study provides insights into the role of combined extended resections in robot-assisted thymic tumor surgery and their impact on outcomes.

## Key findings

- Robot-assisted surgery for thymic tumors achieved a high R0 resection rate of 93.7%.
- Combined extended resections were performed in 30.8% of cases and predicted postoperative complications.
- Most patients had localized disease, with 83.9% in TNM stage I.

## Abstract

Robot‐assisted thoracoscopy (RATS) is rapidly emerging as the preferred approach for the resection of thymic epithelial tumors (TET). Current challenges include the role of RATS in locally advanced disease and combined additional resections.

This single‐center study included all consecutive robot‐assisted surgeries for TET performed between 2018 and 2024. We report perioperative outcomes and findings from a large center for robotic surgery center.

One hundred and forty‐three patients underwent RATS for the resection of histologically confirmed TET, including 130 (91%) patients with thymoma and 13 (9%) patients with thymic carcinoma. The median tumor size was 54 mm (35.5–75) and most patients presented in a localized stage of disease, with 120 patients (83.9%) in TNM stage I (TNM 8th edition). The conversion rate to open surgery was 4.2% and R0 resection was achieved in 134 (93.7%) patients. Combined extended resections that included lung, pericardium or great vessels were performed in 44 (30.8%) patients and were the only independent predictor of postoperative complications in a multivariable logistic regression model (OR 2.87; p = 0.03).

Robot‐assisted surgery is feasible and without unexpected safety concerns for TET. Combined extended resections, often necessary for locally advanced disease, are a significant predictor of postoperative complications.

## Linked entities

- **Diseases:** thymoma (MONDO:0006456), thymic carcinoma (MONDO:0006451)

## Full-text entities

- **Diseases:** TET (MESH:C536905), tumor (MESH:D009369), thymic carcinoma (MESH:D013945)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

31 references — full list in the complete paper: https://tomesphere.com/paper/PMC12989189/full.md

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Source: https://tomesphere.com/paper/PMC12989189