# Small Pontine Infarction Secondary to Posterior Inferior Cerebellar Artery (PICA) Atherosclerosis: The Diagnostic Value of 3 Tesla MRI

**Authors:** Dang Nhat Vo, Tri Dung Ton That, Vy Duyen Duong

PMC · DOI: 10.7759/cureus.103533 · Cureus · 2026-02-13

## TL;DR

A 3 Tesla MRI helped diagnose a small brain infarction caused by PICA atherosclerosis, which is often missed due to vague symptoms like vertigo.

## Contribution

The study highlights the diagnostic value of 3 Tesla MRI in detecting small pontine infarctions linked to PICA atherosclerosis.

## Key findings

- 3 Tesla MRI identified a 5-mm acute ischemic lesion in the left pons using DWI and ADC sequences.
- 3D TOF MRA showed multifocal atherosclerotic stenosis in the left PICA.
- Treatment with DAPT, statins, and blood pressure control led to significant clinical improvement.

## Abstract

Posterior circulation strokes, particularly those involving the posterior inferior cerebellar artery (PICA), often present with nonspecific symptoms, such as vertigo, frequently leading to misdiagnosis as peripheral vestibular disorders. Identifying small lacunar infarcts in these regions requires high-resolution neuroimaging. A 65-year-old female with a history of hypertension and dyslipidemia presented with sudden-onset rotatory vertigo, headache, and right-sided paresthesia (National Institutes of Health Stroke Scale {NIHSS}=2). The 3 Tesla MRI revealed a 5-mm acute ischemic focus in the left pons on diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) sequences. Three-dimensional (3D) time-of-flight (TOF) magnetic resonance angiography (MRA) demonstrated multifocal atherosclerotic stenosis along the left PICA. The patient was managed with dual antiplatelet therapy (DAPT) (clopidogrel 75 mg and aspirin 100 mg), high-intensity statin (rosuvastatin 20 mg), and stringent blood pressure control. Following seven days of treatment, clinical symptoms improved significantly, and the patient was discharged in stable condition. The 3 Tesla MRI is a pivotal tool for detecting small-core infarcts and evaluating detailed atherosclerotic changes in the posterior circulation. Integrating clinical vigilance with advanced imaging facilitates accurate diagnosis and optimizes medical management to prevent recurrent stroke.

## Linked entities

- **Chemicals:** clopidogrel (PubChem CID 2806), aspirin (PubChem CID 2244), rosuvastatin (PubChem CID 446157)
- **Diseases:** dyslipidemia (MONDO:0002525)

## Full-text entities

- **Diseases:** headache (MESH:D006261), atherosclerotic (MESH:D050197), PICA (MESH:D014854), rotatory vertigo (MESH:D014717), lacunar infarcts (MESH:D059409), hypertension (MESH:D006973), atherosclerotic stenosis (MESH:D003251), peripheral vestibular disorders (MESH:D010523), Pontine Infarction (MESH:D007238), dyslipidemia (MESH:D050171), Stroke (MESH:D020521), ischemic (MESH:D002545), Posterior circulation strokes (MESH:D020520), paresthesia (MESH:D010292)
- **Chemicals:** clopidogrel (MESH:D000077144), rosuvastatin (MESH:D000068718), aspirin (MESH:D001241), antiplatelet (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12989168/full.md

## References

8 references — full list in the complete paper: https://tomesphere.com/paper/PMC12989168/full.md

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Source: https://tomesphere.com/paper/PMC12989168