# Vascular contribution to cognitive impairment and dementia (VCID): proceedings of 2025 workshop of the Jackson Laboratory

## TL;DR

A workshop on vascular contributions to dementia was held to foster collaboration and train new scientists in understanding and treating dementia.

## Contribution

The workshop emphasized interdisciplinary collaboration and training to advance VCID and ADRD research through experimental models.

## Key findings

- The workshop highlighted the role of neurovascular pathology in ADRD pathogenesis.
- It emphasized the need to dissect VCID mechanisms through experimental models.
- Keynote addresses by leading experts aimed to inspire and guide future research.

## Abstract

The first Vascular Contributions to Cognitive Impairment and Dementia (VCID) Workshop, held on May12-16, 2025 at The Jackson Laboratory, provided scientific content and career development training in the latest developments in VCID and Alzheimer’s Disease (AD) and related dementia (ADRD). The Workshop aimed to foster interdisciplinary collaborations and empower the next generation of diverse scientists to advance ADRD research from mechanism to intervention. The meeting placed a strong emphasis on neurovascular pathology, its central role in ADRD pathogenesis, its modulation by both central and peripheral factors, and the critical need to dissect the mechanistic basis of VCID through experimental models. The workshop included talks from both faculty and trainees and was bookended by two keynote addresses by Drs. Donna Wilcock and Costantino Iadecola, leaders and pioneers in the VCID field. The second VCID workshop is planned for April 28-May 1, 2026, to be held at Washington University in St. Louis.