# Endoscopic Debulking in the Management of Osteosarcoma With a Rare Endobronchial Metastasis

**Authors:** Jeffrey S Jang, Ghita Bouzarif, David W Hsia

PMC · DOI: 10.7759/cureus.103501 · Cureus · 2026-02-12

## TL;DR

This paper presents a rare case of osteosarcoma with a central lung tumor managed through endoscopic debulking and chemotherapy.

## Contribution

The paper highlights a rare endobronchial metastasis of osteosarcoma and its multidisciplinary treatment approach.

## Key findings

- Endoscopic debulking was used to manage a central airway tumor caused by osteosarcoma metastasis.
- The patient was later treated medically with chemotherapy to control tumor burden.
- This case emphasizes the need for individualized treatment in rare metastatic presentations.

## Abstract

Osteosarcoma most commonly metastasizes to the lung, which requires individualized management based on the location of the disease. Surgical resection has been the cornerstone to improving outcomes in peripheral metastatic lung disease. However, central airway obstruction is rare, resulting in limited evidence regarding the optimal management of this manifestation. We report a case of a 68-year-old man with osteosarcoma and bilateral lung metastasis. A 10 centimeter tumor on the right involved the hilum with extension to the pleura. Bronchoscopy confirmed an endobronchial mass occluding the bronchus intermedius. This central airway tumor was debulked via endoscopy and later managed medically with chemotherapy. This case describes a rare manifestation of osteosarcoma metastasis and the multidisciplinary management to control tumor burden.

## Linked entities

- **Diseases:** osteosarcoma (MONDO:0002623)

## Full-text entities

- **Diseases:** Osteosarcoma (MESH:D012516), lung disease (MESH:D008171), airway obstruction (MESH:D000402), Endobronchial Metastasis (MESH:D009362), airway tumor (MESH:D009369)

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12988857/full.md

## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12988857/full.md

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Source: https://tomesphere.com/paper/PMC12988857