# Sudden Death of a 17‐Month‐Old Chimpanzee ( Pan troglodytes ) due to a Congenital Undiagnosed Ventricular Septal Defect

**Authors:** Ivanela Kondova, Merel Langelaar, Arno A. W. Roest, Peter J. Heidt

PMC · DOI: 10.1111/jmp.70070 · Journal of Medical Primatology · 2026-03-13

## TL;DR

A 17-month-old chimpanzee suddenly died from an undiagnosed heart defect similar to those seen in humans.

## Contribution

This case highlights the occurrence of undiagnosed VSD in non-human primates leading to sudden death.

## Key findings

- The chimpanzee had a congenital ventricular septal defect (VSD).
- The heart showed left ventricular dilatation and right ventricular hypertrophy.
- The VSD was not diagnosed before the sudden death of the infant.

## Abstract

Ventricular septal defect (VSD) is a congenital defect that is frequently observed in humans. We report the sudden death of an infant chimpanzee due to a congenital undiagnosed VSD. During necropsy, the examination of the heart revealed a VSD, dilatation of the left ventricle and myocardial hypertrophy of the right ventricle.

## Linked entities

- **Diseases:** ventricular septal defect (MONDO:0002070)
- **Species:** Pan troglodytes (taxon 9598)

## Full-text entities

- **Diseases:** dead (MESH:D001926), heart failure (MESH:D006333), pulmonary hypertension (MESH:D006976), myocardial hypertrophy (MESH:D006984), failure of (MESH:D051437), congenital abnormalities (MESH:D000013), inflammatory (MESH:D007249), VSD (MESH:D006345), dilatation of the left ventricle (MESH:D020257), CHDs (MESH:D006330), hypertrophied right ventricle (MESH:D017380), haemorrhage (MESH:D006470), death (MESH:D003643), disturbances of blood flow (MESH:D054318), failure to thrive (MESH:D005183), Sudden Death (MESH:D003645), heart murmur (MESH:D006337), breathlessness (MESH:D004417)
- **Chemicals:** H&amp;E (MESH:D006371), oxygen (MESH:D010100)
- **Species:** Pongo abelii (orang utan, species) [taxon 9601], Equus caballus (domestic horse, species) [taxon 9796], Alocasia macrorrhizos (ape, species) [taxon 4456], Bos taurus (bovine, species) [taxon 9913], Gorilla gorilla gorilla (lowland gorilla, subspecies) [taxon 9595], Macaca radiata (bonnet macaque, species) [taxon 9548], Homo sapiens (human, species) [taxon 9606], Pan troglodytes (chimpanzee, species) [taxon 9598]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12988023/full.md

## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12988023/full.md

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Source: https://tomesphere.com/paper/PMC12988023