# The Effect of Novel Low-Dose Caffeine Products on Physical Performance

**Authors:** Andrew Thomas Hulton, Isobel Staines, Oscar Clark, Arun Subramaniam, James Matt Green

PMC · DOI: 10.3390/nu18050791 · Nutrients · 2026-02-27

## TL;DR

This study explores how low-dose caffeine products affect physical performance, finding potential benefits in strength endurance.

## Contribution

The study investigates novel low-dose caffeine delivery methods and their impact on physical performance metrics.

## Key findings

- Low-dose caffeine pouch showed moderate effects on strength endurance compared to placebo.
- Caffeine reduced perceived exertion during physical tasks.
- No significant differences were found in physical tests across conditions.

## Abstract

Background: Caffeine is an ergogenic aid shown to delay fatigue, increase arousal, and improve performance. Recommended doses are 3–6 mg/kg BM, although evidence supports lower doses (<3 mg/kg). Some conflicting results have highlighted that lower doses may still be ergogenic, and with new pouch and gum products, further research is warranted. Method: This study investigated the effects of novel low-dose caffeine products on muscular endurance, strength, and power. A repeated-measure, crossover design (pouch 80 mg, gum 80 mg, control gum 0 mg) was employed, recruiting nineteen participants (age 22.4 + 4.8 yrs; weight 72.8 + 16.9 kg; relative caffeine dose 1.1 mg/kg). Participants completed a battery of tests, including 60% 1 RM single leg press (LP) and shoulder press (SP) to exhaustion, counter-movement jump, and isometric mid-thigh pull, in addition to providing ratings of perceived exertion (RPE) during endurance tests. One-way repeated measures ANOVA was conducted on all measures associated with physical tasks, with a two-way repeated measures ANOVA conducted for RPE. Results: No significance was observed among conditions for physical tests. However, effect sizes, employing Cohen’s D classification, identified a moderate (d = 0.55) and small (d = 0.45) effect for the caffeine pouch compared to the placebo and caffeine gum for the LP respectively. Further, small effects for the pouch compared to the placebo were observed (d = 0.33) for the SP. Significant differences were produced for RPE during the LP (p = 0.022), with post hoc analysis identifying significant differences between the placebo vs. caffeine pouch (p = 0.032). Conclusion: Low-dose caffeine has the potential to produce meaningful effects on strength endurance, likely linked to caffeine mechanisms reducing RPE.

## Linked entities

- **Chemicals:** caffeine (PubChem CID 2519)

## Full-text entities

- **Diseases:** fatigue (MESH:D005221)
- **Chemicals:** Caffeine (MESH:D002110)

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12987369/full.md

## References

68 references — full list in the complete paper: https://tomesphere.com/paper/PMC12987369/full.md

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Source: https://tomesphere.com/paper/PMC12987369